The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones +14 more
wiley +1 more source
Lactose Engineering for Better Performance in Dry Powder Inhalers [PDF]
Dry powder inhaler (DPI) is generally formulated as a powder mixture of coarse carrier particles and micronized drug with aerodynamic diameters of 1-5 μm.
Yahya Rahimpour, Hamed Hamishehkar
doaj
Salbutamol powder inhaled from the Diskhaler compared to salbutamol as nebulizer solution in severe chronic airways obstruction [PDF]
The bronchodilatory effect of four doses of salbutamol powder (1·6 mg) from a multi-dose dry powder inhaler, the Diskhaler, was compared to the effect of 2·5 ml salbutamol nebulizer solution (1 mg ml−1) from a jet nebulizer, Pari Inhalierboy, in a ...
Buijs, Pascal +5 more
core +7 more sources
Growth Hormone‐Loaded 3D Printed Silk Fibroin‐Cellulose Dressings for Ischemic Wounds
3D‐printed wound dressings combining carboxymethyl cellulose, silk fibroin, and growth hormone accelerate healing in diabetic ulcers. These bioactive, customizable dressings enhance angiogenesis, cellular proliferation, and immune modulation. Proteomic analysis reveals activation of regenerative pathways and reduced fibrosis, highlighting their ...
Maria Pita‐Vilar +7 more
wiley +1 more source
Differences In Therapeutic Efficacy Between Pressurized Metered-dose Inhaler And Dry Powder Inhaler For Asthma Patients With Small Airway Dysfunction [PDF]
Susumu Fukahori +5 more
openalex +1 more source
Распадаемость агломератов в процессе высвобождения из ингалятора [PDF]
Представлены результаты экспериментальных исследований фракционного состава микронизированной активной фармацевтической субстанции Сальметерола ксинафоат при выходе из однодозового порошкового ингалятора.
Иванов, Н. А. +2 more
core +2 more sources
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales +11 more
wiley +1 more source
Excipient-API interactions in dry powder inhalers
There remains a paucity of predictive models to evaluate the suitability of excipients or excipient mixtures for dry powder inhalers because a large number of interdependent variables affect both formulation and inhaler performance.
Shireesh Apte
doaj
The comparative effectiveness of initiating fluticasone/salmeterol combination therapy via pMDI versus DPI in reducing exacerbations and treatment escalation in COPD: a UK database study [PDF]
Rupert Jones,1 Jessica Martin,2 Vicky Thomas,3 Derek Skinner,4 Jonathan Marshall,5 Martina Stagno d’Alcontres,2 David Price2,6 1Clinical Trials and Health Research, Institute of Translational and Stratified Medicine, Plymouth University Peninsula ...
Jones, R +6 more
core +2 more sources
Hybrid Nanofibers for Multimodal Accelerated Wound Healing
Fabrication of wound healing scaffolds based on biocompatible nanofibers. Nanofibers offering high surface area, flexibility, and biocompatibility significantly improved the healing outcome in vivo. Histological, immunological, and anti‐inflammatory markers are noticeably better in treated wounds.
Viraj P. Nirwan +15 more
wiley +1 more source

