Results 61 to 70 of about 718,991 (267)

Geospatial analysis of trace metal pollution and ecological risks in river sediments from agrochemical sources in Morocco’s Sebou basin

Scientific Reports
Sediments in agricultural ecosystems serve as critical indicators of environmental pollution, particularly in regions subjected to intensive agricultural practices.
Hatim Sanad, Rachid Moussadek, Latifa Mouhir, Majda Oueld Lhaj, Houria Dakak, Abdelmjid Zouahri   +5 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

A two-step dry process for Cs2SnI6 perovskite thin film

Materials Research Letters, 2017
A two-step process for synthesizing stable Cs2SnI6 perovskite thin films is reported in this letter. The two-step process includes the co-evaporation of two precursors SnI2 and CsI onto a glass substrate, followed by a post thermal annealing process in ...
Fawen Guo, Zonghuan Lu, Dibyajyoti Mohanty, Tianmeng Wang, Ishwara B. Bhat, Shengbai Zhang, Sufei Shi, Morris A. Washington, Gwo-Ching Wang, Toh-Ming Lu   +9 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

MACROKINETIC INVESTIGATIONS OF DRY FLUE-GAS DESULFURIZATION PROCESS USING TGA TECHNIQUE

Studia Universitatis Babes-Bolyai Chemia, 2018
In this paper, a kinetic study about of dry flue-gas desulfurization process was investigated. Experimental thermogravimetric measurements, employing a CAHN TG- 121 system, have been performed on the reaction of sulfur dioxide and oxygen with calcined ...
Simion DRĂGAN
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Sustainable Agriculture Through Agricultural Waste Management: A Comprehensive Review of Composting’s Impact on Soil Health in Moroccan Agricultural Ecosystems

Agriculture
Agricultural activities generate substantial quantities of waste, which are often relegated to landfills or incineration. However, these residues can be effectively valorized through composting, which transforms them into valuable organic fertilizers (OF)
Majda Oueld Lhaj, Rachid Moussadek, Abdelmjid Zouahri, Hatim Sanad, Laila Saafadi, Meriem Mdarhri Alaoui, Latifa Mouhir   +6 more
doaj   +1 more source

Ultrahigh loading dry-process for solvent-free lithium-ion battery electrode fabrication. [PDF]

Nat Commun, 2023
Ryu M, Hong YK, Lee SY, Park JH.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source