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Cutaneous Neuroimmune Interactions of TSLP and TRPV4 Play Pivotal Roles in Dry Skin-Induced Pruritus [PDF]

open access: yesFrontiers in Immunology, 2021
Dry skin is a symptom of skin barrier dysfunction that evokes pruritus; however, the cutaneous neuroimmune interactions underlying dry skin-induced pruritus remain unclear.
Wook-Joo Lee   +3 more
doaj   +3 more sources

Mechanisms and Management of Itch in Dry Skin [PDF]

open access: yesActa Dermato-Venereologica, 2020
Chronic itch is a burdensome clinical problem that often accompanies pathological dry skin-based conditions, such as atopic dermatitis, and systemic disorders, such as kidney diseases, with an unclear pathomechanism and treatments. One of the basic mouse
Catharina Sagita Moniaga   +2 more
doaj   +4 more sources

Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Erlotinib Induces Dry Skin via Decreased in Aquaporin-3 Expression [PDF]

open access: yesBiomolecules, 2020
An adverse reaction of dry skin occurs frequently during treatment with anticancer epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs).
Nobutomo Ikarashi   +9 more
doaj   +3 more sources

Relationship between dry skin and pressure injury in older patients: A multicentre cross-sectional survey in China. [PDF]

open access: yesInt Wound J, 2023
Dry skin and pressure injuries in older persons have become global health care problems. This was a multicentre, prospective cross‐sectional study in 44 hospitals and 8 long term care institutions from 20 provinces, autonomous regions and municipalities ...
Jiang Q   +11 more
europepmc   +2 more sources

IL-33 signaling in sensory neurons promotes dry skin itch. [PDF]

open access: yesJ Allergy Clin Immunol, 2022
BACKGROUND Chronic pruritus, or itch, is common and debilitating, but the neuro-immune mechanisms that drive chronic itch are only starting to be elucidated.
Trier AM   +22 more
europepmc   +2 more sources

Ingested hyaluronan moisturizes dry skin. [PDF]

open access: yesNutr J, 2014
Hyaluronan (HA) is present in many tissues of the body and is essential to maintain moistness in the skin tissues, which contain approximately half the body's HA mass. Due to its viscosity and moisturizing effect, HA is widely distributed as a medicine, cosmetic, food, and, recently marketed in Japan as a popular dietary supplement to promote skin ...
Kawada C   +10 more
europepmc   +5 more sources

Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin. [PDF]

open access: yesSci Rep, 2022
Xerosis, commonly referred to as dry skin, is a common dermatological condition affecting almost a third of the population. Successful treatment of the condition traditionally involves the application of cosmetic products facilitating the moisturisation ...
Murphy B   +18 more
europepmc   +2 more sources

Reliability and validity of the Japanese version of the overall dry skin score in older patients. [PDF]

open access: yesSkin Res Technol, 2022
Dry skin is the most common skin problem, especially in the elderly. However, there is no effective instrument to assess dry skin in Japan. This study aimed to evaluate the reliability and validity of the Japanese version of the overall dry skin score ...
Konya I   +6 more
europepmc   +2 more sources

Spinal cord NLRP1 inflammasome contributes to dry skin induced chronic itch in mice. [PDF]

open access: yesJ Neuroinflammation, 2020
Background Dry skin itch is one of the most common skin diseases and elderly people are believed to be particularly prone to it. The inflammasome has been suggested to play an important role in chronic inflammatory disorders including inflammatory skin ...
Fan JJ   +7 more
europepmc   +2 more sources

Oral and Topical Centella asiatica in Type 2 Diabetes Mellitus Patients with Dry Skin: A Three-Arm Prospective Randomized Double-Blind Controlled Trial. [PDF]

open access: yesEvid Based Complement Alternat Med, 2020
Introduction Uncontrolled diabetes mellitus (DM) is related to skin disorders, particularly dry skin. Pathogenesis of dry skin in type 2 diabetes mellitus (T2DM) rises from the chronic hyperglycemia causing an increase in advanced glycation end-products (
Legiawati L   +9 more
europepmc   +2 more sources

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