Results 41 to 50 of about 1,919,764 (290)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Sweet corn windbreaker’s effect on microweather changes and increases growth and yield of water spinach (Ipomoea reptans Poir.) on the Samas coastal sandy land

Ilmu Pertanian (Agricultural Science)
High wind speed is one of the limiting factors for plant cultivation in coastal sandy land. To mitigate this, sweet corn, an annual plant, can be cultivated as a windbreaker. Water spinach is one of the short-lived plants cultivated by farmers in coastal
Fajarani Ulfah, Didik Indradewa, Dyah Weny Respatie   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Co-application of compost and biochar improves soil properties and Desho grass growth on acidic soils in a tropical environment of Southwestern Ethiopia

Cogent Food & Agriculture
Organic soil amendments offer promising potential to improve soil properties and plant growths. However, data on these benefits of compost and biochar in a tropical environment are limited.
Seyifu Shifa, Mohammed Worku, Abegaz Beyene   +2 more
doaj   +1 more source

Biopriming with Trichoderma on Germination and vegetative characteristics of sweet corn, sugar beet and wheat [PDF]

علوم و فناوری بذر ایران, 2020
The present study was conducted to investigate the effect of biopriming on a number of selected species of Trichoderma fungi (T. harzianum, T. viride, T. konigii, T. virens and T.
zahra rezaloo, samira shahbazi, hamed askari   +2 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Effects end of seasonal drought stress on germination parameters and seedling heterotrophic growth of wheat cultivars [PDF]

علوم و فناوری بذر ایران, 2020
In order to investigate the effect of drought stress on germination parameters and heterotrophic growth of different wheat cultivars, a factorial experiment was carried out in a completely randomized design with 6 replications in a research greenhouse of
Zohreh Molavi, Abbas Biabani, Ali Nakhzari Moghadam, ali rahemi-karizaki   +3 more
doaj   +1 more source

Comparison of four methods for quantification of biofilms in biphasic cultures [PDF]

, 1998
Three methods for determining the total biofilm amount in biphasic cultures have been compared: dry weight by filtration after solvent treatment, optical density with a biomass probe and protein content.
Délia, Marie-Line, Joannis-Cassan, Claire, Riba, Jean-Pierre   +2 more
core   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source