Results 51 to 60 of about 1,929,417 (311)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The feasibility of using compression bioimpedance measurements to quantify peripheral edema
Journal of Electrical Bioimpedance, 2014 The accurate assessment of body fluid volume is important in many clinical situations, especially in the determination of “dry weight” in a dialysis setting.
Koziol Leo +6 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Plants, 2023 Weed infestation is a prime challenge coupled with lowering crop production owing to their competition with crop plants for available resources such as nutrients, water, space, moisture, and sunlight.
Muhammad Shahid Hassan +10 more
doaj +1 more source
Seasonal Variation in Leaf Growth and Antioxidant Content of Moringa oleifera Cultivated at Buenos Aires, Argentina [PDF]
, 2016 The properties and applications of Moringa oleifera are so vast that it is called the "miracle tree". The objective of this work is to study the seasonal variations in the leaf antioxidant content and the scavenging activity on DPPH radicals in ...
Arena, Miriam Elisabet, Radice, Silvia
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
The durability of negative effects of silver nanoparticles on seed germination and growth characteristics of Scots pine (Pinus sylvestris L.) in soil [PDF]
تحقیقات جنگل و صنوبر ایران, 2018 This study was conducted on the stability of the inhibitory effects of Ag nano-particles on seed germination and growth characteristic of Scots pine (Pinus sylvestris L.) seeds planted in soil.
Vilma Bayramzadeh +4 more
doaj +1 more source
Establishing a rapid and effective method for screening salt tolerance in soybean [PDF]
, 2009 Chlorine (Cl) toxicity has been recognized as a constraint for soybean production. Although the use of a Cl-tolerant crop easily solves the problem, current screening methodologies for Cl tolerance are often ineffective because of inadequate means of ...
Chen, Pengyin, Tamura, Mioko
core +2 more sources
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source