Results 91 to 100 of about 905,896 (362)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Modeling and Effects of Various Drying Methods on Sweet Potato Starch Properties

Walailak Journal of Science and Technology, 2011
Eleven mathematical models (Lewis, Page, Henderson and Pabis, modified Henderson and Pabis, Wang and Singh, logarithmic, two term, two term exponential, Midilli, approximation of diffusion and Verma et al, model) were used for describing the drying ...
Ho Minh THAO, Athapol NOOMHORM
doaj   +1 more source

An assessment of environmental impacts of cassava starch extraction technologies [PDF]

, 2011
The environmental impacts of the transformation of cassava roots into starch were assessed for three contrasting technologies at small and large scale (1-2 and 100-200t starch per day), using the Life Cycle Assessment (LCA) methodology. The objective was
Da, Guillaume, Dufour, Dominique, Giraldo Toro, Andres, Moreno, Martin A., Piyachomkwan, Kuakoon, Sriroth, Klanarong, Tran, Thierry, Velez, G.   +7 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Effect of Extraction Solvents and Drying Methods on the Physicochemical and Antioxidant Properties of Helicteres hirsuta Lour. Leaves

Technologies, 2015
Helicteres hirsuta Lour. (H. hirsuta L.) is widely distributed in southeast Asian countries and has been used traditionally as a medicinal plant. However, optimal conditions for preparation of dried materials for further processing and suitable solvents ...
Hong Ngoc Thuy Pham, Van Tang Nguyen, Quan Van Vuong, Michael C. Bowyer, Christopher J. Scarlett   +4 more
doaj   +1 more source

Method for Particle Size Control During the Drying and Granulation in Fluidized Bed [PDF]

, 2001
The fluidized bed process presented in this paper is suitable for recovery of solids from solutions in the form of granules. The solution is sprayed into the bed and as solvent evaporates, solid material is deposited on the surface of fluidizing ...
Dencs, B., Gyenis, János, Tardos, I. G.
core  

Krylov subspace approximations for the exponential Euler method: error estimates and the harmonic Ritz approximant [PDF]

, 2011
We study Krylov subspace methods for approximating the matrix-function vector product φ(tA)b where φ(z) = [exp(z) - 1]/z. This product arises in the numerical integration of large stiff systems of differential equations by the Exponential Euler Method ...
Carr, Elliot, Ilic, Milos, Turner, Ian
core   +3 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Effects of Different Drying Methods on Nutritional Components, Antioxidant Activity and Volatile Components of Five Kinds of Dried Figs

Shipin gongye ke-ji
Drying methods may cause changes in the color and texture of figs, accelerating the loss of nutrients. In this study, five fig varieties ('Boji red' 'Orphan' 'Zhongzi' 'Qingpi' and 'Xinjiang Zaohuang') were used as research subjects.
Zhenzhen DING, Na XIA, Yanquan LIU, Tian ZHANG, Lei JIANG, Yanchang WANG, Chao ZHANG   +6 more
doaj   +1 more source

ANALISIS PENJADWALAN PRODUKSI DENGAN METODE NETWORK PLANNING (CRITICAL PATH METHOD) UNTUK EFEKTIVITAS WAKTU PRODUKSI DRYING OVEN 200O C DI CV. JUNTI MANDIRI UTAMA [PDF]

, 2017
ABSTRAK Penjadwalan setiap perusahaan merupakan hal yang sangat penting untuk dilakukan.Salah satu metode yang dapat digunakan dalam penjadwalan adalah metode Network Planning (Critical Path Method). CV.
Muhammad Yudha Arifin, 134010365, Pembimbing I, Wasito, SE., MSIE.   +1 more
core