Results 91 to 100 of about 2,849,574 (209)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Mechanistic modeling of primary drying of frozen particulates

AAPS Open
Thin-film freeze-drying (TFFD) produces discrete, millimeter-scale frozen particles under highly controlled conditions, yielding beds with reproducible structure and distinctive drying kinetics.
Benjamin Southard, Robin Bogner, Robert O. Williams III, Zhengrong Cui   +3 more
doaj   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Modeling fixed-bed drying of bark

, 2017
A model for fixed-bed drying of bark has been developed. The model takes heat and mass transfer between the air and bark into account and the volumetric heat transfer coefficient was used as fitting parameter in the model.
Holmberg, André,, Stenström, Stig,, Huttunen, Marcus,, Lund University.   +3 more
core   +2 more sources

Bee Bread Granule Drying in a Solar Dryer with Mobile Shelves

Energies
This paper presents the development and evaluation of an autonomous solar dryer designed to enhance the drying efficiency of bee bread granules.
Indira Daurenova, Ardak Mustafayeva, Kanat Khazimov, Francesco Pegna, Marat Khazimov   +4 more
doaj   +1 more source

Drying kinetics and thermodynamic properties of guava peel [PDF]

Ciência Rural
: The drying agroindustrial products is used to preserve the sensory and nutritional quality and to reduce the biological activity, preventing deterioration and loss of commercial value.
Lígia Campos de Moura Silva, Diene Gonçalves Souza, Abner Alves Mesquita, Esther Cristina Neves Medeiros, Viviane Patrícia Romani, Márcio Caliari, Geovana Rocha Plácido, Osvaldo Resende, Daniel Emanuel Cabral de Oliveira, Marco Antônio Pereira da Silva   +9 more
doaj   +1 more source

Multi-scale model of food drying: Current status and challenges [PDF]

, 2016
For a long time, food engineers have been trying to describe the physical phenomena that occur during food processing especially drying. Physics-based theoretical modeling is an important tool for the food engineers to reduce the hurdles of ...
Khan, M.I.H., Rahman, M.M., Joardder, Mohammad U.H., Pham, Nghia Duc, Karim, M.A.   +4 more
core   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source