Results 71 to 80 of about 3,329 (189)

Disorders of sex development: A 10 years experience with 73 cases from the Kashmir Valley

Indian Journal of Endocrinology and Metabolism, 2019
Purpose: To present the clinical data, investigative profile, and management of patients with disorders of sex development (DSD) from the endocrine unit of a tertiary care university hospital.
Raiz Ahmad Misgar, Moomin Hussain Bhat, Shariq Rashid Masoodi, Mir Iftikhar Bashir, Arshad Iqbal Wani, Aejaz Ahsan Baba, Gowhar Nazir Mufti   +6 more
doaj   +1 more source

A user‐friendly goniometer‐compatible fixed‐target platform for macromolecular crystallography at synchrotrons

Journal of Applied Crystallography, EarlyView.
A user‐friendly fixed‐target platform for serial synchrotron crystallography is described, which allows low‐background X‐ray diffraction data collection, in situ crystallization and transportation of protein microcrystals at room temperature.Fixed‐target platforms provide convenient support for microcrystals during serial X‐ray crystallography studies ...
Swagatha Ghosh, Analia Banacore, Per Norder, Monica Bjelčić, Arpitha Kabbinale, Padmini Nileshwar, Gabrielle Wehlander, Daniele de Sanctis, Shibom Basu, Julien Orlans, Adams Vallejos, Leonard M. G. Chavas, Richard Neutze, Gisela Brändén   +13 more
wiley   +1 more source

Bayesian perspective for orientation determination in cryo‐EM with application to structural heterogeneity analysis

Acta Crystallographica Section D, EarlyView.
A Bayesian perspective on orientation estimation in cryo‐EM is presented, with the minimum mean‐square error estimator outperforming standard cross‐correlation‐based approaches, particularly under challenging low signal‐to‐noise conditions. We demonstrate that improved orientation estimation has a decisive impact on 3D reconstruction quality and ...
Sheng Xu, Amnon Balanov, Amit Singer, Tamir Bendory   +3 more
wiley   +1 more source

Research progress in the role of DHX37 gene in disorders of sex development

Shanghai Jiaotong Daxue xuebao. Yixue ban
Disorders of sex development (DSD) are a group of conditions with strong clinical phenotype heterogeneity, and the incidence of DSD in the population is 1/5 000 to 1/4 500.
LIU Bei, HE Jing
doaj   +1 more source

A SWOT Analysis of Three Programmes for Persons With Intellectual Disabilities in Higher Education Settings in Chile, Ireland and Australia

British Journal of Learning Disabilities, EarlyView.
ABSTRACT Background Educational access is key in empowering persons living with intellectual disabilities. Nevertheless, internationally, Persons with Intellectual Disabilities continue to experience marginalization and discrimination in accessing higher education.
Denise De Souza, Zelinna Pablo, Debashis Sarker, Maria Theresa von Fürstenberg, Alejandra Rios Urzua, Des Aston, Jennifer Banks, Donatella Camedda, Michael Shevlin   +8 more
wiley   +1 more source

Raindrop Size Distribution Retrieval Using Joint Dual-Frequency and Dual-Polarization Microwave Links

Advances in Meteorology, 2019
Estimation of raindrop size distribution (DSD) is essential in many meteorological and hydrologic fields. This paper proposes a method for retrieving path-averaged DSD parameters using joint dual-frequency and dual-polarization microwave links of the ...
Kun Song, Xichuan Liu, Taichang Gao, Binsheng He   +3 more
doaj   +1 more source

Safety, tolerability, pharmacokinetics and pharmacodynamics of the spleen tyrosine kinase inhibitor BI 894416 in healthy volunteers and patients with asthma

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Spleen tyrosine kinase (SYK) has broad biological functions in inflammation and immunity. The orally administered SYK inhibitor BI 894416 was investigated in a single‐rising‐dose Phase I study in healthy volunteers and in a combined single‐ and multiple‐rising‐dose Phase Ib study in patients with mild asthma ...
Saskia Carstensen‐Aurèche, Tobias Litzenburger, Dorothy De Sousa, Reinhard Sailer, Ewald Benediktus, Denis Delic, Fabian Müller, Meike Müller, Jens M. Hohlfeld   +8 more
wiley   +1 more source

A novel holographic framework preserving reflection positivity in dSd spacetime

Physics Letters B
This manuscript introduces a novel holographic correspondence in d-dimensional de Sitter (dSd) spacetime, connecting bulk dSd scalar unitary irreducible representations (UIRs) with their counterparts at the dSd boundary I±, all while preserving ...
Jean-Pierre Gazeau, Mariano A. del Olmo, Hamed Pejhan   +2 more
doaj   +1 more source

eP221: Increased expression of ZFPM2 bypasses SRY to drive 46,XX testicular development: A new mechanism of 46,XX DSD [PDF]

, 2022
Leah Ragno, Daphne Yang, Trisha Bhatti, Jonathan P. Bradfield, Diane K. Bowen, Katheryn Grand, Håkon Håkonarson, Thomas F. Kolon, Joseph Glessner, M. Celeste Simon, Nicolas Skuli, Maria G. Vogiatzi, Marie Guerraty, Matthew A. Deardorff, Louise C. Pyle   +14 more
openalex   +1 more source

Measures to Ensure That Social Workers Render Holistic Family Reunification Services: A South African Perspective

Children &Society, EarlyView.
ABSTRACT Placement of children in alternative care is supposed to be a temporary arrangement while social workers address issues that led to the removal of a child from the care of the family. However, in the rendering of family reunification services (FRS), social workers encounter numerous challenges that hinder their ability and capacity to render ...
Sipho Sibanda
wiley   +1 more source