Results 91 to 100 of about 342,507 (303)

Asignaturas pendientes del DSM-5 [PDF]

, 2015
El presente artículo analiza las críticas generadas a partir de la publicación del Manual diagnóstico y estadístico de los trastornos mentales, quinta edición (DSM-5), ya anunciadas parcialmente durante las últimas fases de su elaboración.
Artigas, Josep, 1948-, Paula Pérez, Isabel, 1970-   +1 more
core  

Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression

Advanced Science, EarlyView.
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai, Taipeng Sun, Mengzhen Feng, Gang Chen, Junchi Zhou, Hong Zhuang, Dan Wang, Ying Chen, Zhen Cheng, Zhi Xu, Xiao Zheng, Xueli Zhang, Yonggui Yuan   +12 more
wiley   +1 more source

Prevalence and correlates of DSM-5 major depressive and related disorders in the community. [PDF]

, 2017
Although the DSM-5 has suggested the two new categories of Persistent Depressive Disorders (PDD) and Other Specified Depressive Disorders (OSDD), no study so far has applied the DSM-5 criteria throughout the range of depressive disorders. The aims of the
Angst, J., Aubry, J.M., Castelao, E., Fassassi, S., Gebreab, S., Glaus, J., Lasserre, A.M., Pistis, G., Preisig, M., Rudaz, D., Strippoli, M.F., Vandeleur, C.L.   +11 more
core   +3 more sources

Screening and assessment tools for gaming disorder: A comprehensive systematic review [PDF]

, 2020
The inclusion of gaming disorder (GD) as an official diagnosis in the ICD-11 was a significant milestone for the field. However, the optimal measurement approaches for GD are currently unclear.
Achab, S, Achab, S, Billieux, J, Billieux, J, Brand, M, Brand, M, Carragher, N, Carragher, N, Chamberlain, SR, Chamberlain, SR, Delfabbro, PH, Delfabbro, PH, Demetrovics, Z, Demetrovics, Z, Fineberg, NA, Fineberg, NA, Higuchi, S, Higuchi, S, King, DL, King, DL, Kyrios, M, Kyrios, M, Lee, HK, Lee, HK, Lemenager, T, Lemenager, T, Lindenberg, K, Lindenberg, K, Mueller, K, Mueller, K, Pallesen, S, Pallesen, S, Potenza, MN, Potenza, MN, Rumpf, HJ, Rumpf, HJ, Saunders, J, Saunders, J, Spada, M, Spada, M, Starcevic, V, Starcevic, V, Stein, D, Stein, D, Wu, AMS, Wu, AMS   +45 more
core   +6 more sources

Protein Language Model‐Guided Engineering of a 2,3‐Butanediol Dehydrogenase for the Enantioselective Synthesis of Cyclic α‐Hydroxy Ketones

Advanced Science, EarlyView.
A (2R,3R)‐butanediol dehydrogenase from Bacillus subtilis (BsBDH) is engineered for the enantioselective synthesis of 2‐hydroxycyclohexanone. A PASS computational design strategy is proposed to enhance the thermostability of BsBDH. Moreover, ESM‐1v combined with ISM is utilized for enhancing and inverting its stereoselectivity.
Haote Ding, Ling Jiang, Yijia Song, Zhongji Pu, Lirong Yang, Haoran Yu   +5 more
wiley   +1 more source

Internet gaming disorder: Inadequate diagnostic criteria wrapped in a constraining conceptual model [PDF]

, 2017
The paper “Chaos and confusion in DSM-5 diagnosis of Internet Gaming Disorder: Issues, concerns, and recommendations for clarity in the field” by Kuss, Griffiths, and Pontes (in press) critically examines the DSM-5 diagnostic criteria for Internet gaming
Starcevic, Vladan
core   +1 more source

Light Therapy Alleviates Addiction‐Related Symptoms and Reshapes Habenula and Midbrain Pathways

Advanced Science, EarlyView.
This study investigates light therapy for treating Internet Gaming Disorder (IGD). Functional MRI (fMRI) data reveal that light therapy enhances brain connectivity, particularly between the habenula and the medial orbitofrontal cortex (mOFC). These changes are associated with reduced withdrawal symptoms and addiction severity, highlighting the ...
Jinhui Li, Huiyang Huang, Cunhao Hu, Xuan Zhang, Song Lin, Xiaodan Huang, Ti‐fei Yuan, Kwok‐Fai So, Lu Huang, Chaoran Ren, Qian Tao   +10 more
wiley   +1 more source

Ontologies, Mental Disorders and Prototypes [PDF]

, 2019
As it emerged from philosophical analyses and cognitive research, most concepts exhibit typicality effects, and resist to the efforts of defining them in terms of necessary and sufficient conditions.
A Lieto, American Psychiatric Association, American Psychiatric Association, Antonio Lieto, C Boorse, E Machery, E Rosch, E Rosch, G Murphy, I Horrocks, IR Galatzer-Levy, J Fodor, JC Wakefield, JC Wakefield, K Sadegh-Zadeh, K Sadegh-Zadeh, K Sadegh-Zadeh, L Wittgenstein, M Frixione, M Frixione, M Frixione, M Frixione, MC Amoretti, MC Amoretti, N Pickering, N Pickering, P Gärdenfors, R Brachman, R Cooper, R McNally, R Seising, SO Lilienfeld, SO Lilienfeld, W Ceusters   +33 more
core   +1 more source

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

Advanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li, Jian Wu, Sheng‐Yang Zhou, Ming‐An Li, Li‐Ping Zhao, Ao Wang, Yi‐Zhi Song, Wen‐Yan Huang, Lu‐Lu Tan, Chen‐Meng Qiao, Wei‐Jiang Zhao, Chun Cui, Yan‐Qin Shen   +12 more
wiley   +1 more source

DSM-5 and ICD-11 as competing models of PTSD in preadolescent children exposed to a natural disaster: assessing validity and co-occurring symptomatology

European Journal of Psychotraumatology, 2017
Background: Major revisions have been made to the DSM and ICD models of post-traumatic stress disorder (PTSD). However, it is not known whether these models fit children’s post-trauma responses, even though children are a vulnerable population following ...
Annette M. La Greca, BreAnne A. Danzi, Sherilynn F. Chan   +2 more
doaj   +1 more source