Results 151 to 160 of about 356,850 (303)

Virtual Twin Approach Using Physiologically Based Pharmacokinetic Modeling to Support Precision Dosing of Valproic Acid in Geriatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Personalized dosing is particularly important for drugs with narrow therapeutic indices in geriatric patients, who exhibit substantial physiological variability and limited pharmacokinetic (PK) evidence to guide individualized dose selection. Valproic acid (VPA) is an effective treatment option for bipolar disorder in older adults, yet dosing largely ...
Yoo Jin Jang, Dong‐Gyu Heo, Eunjin Hong   +2 more
wiley   +1 more source

Hours Since Last Drink Is Associated With Multiple Urine Ethyl Glucuronide Cutoffs Among Individuals With Alcohol Use Disorder

Drug Testing and Analysis, EarlyView.
Higher uEtG results indicated more recent drinking, rather than higher levels of alcohol consumption, and the period of detection of uEtG was shorter than previously reported. Even at low cutoffs, uEtG was best conceptualized as a measure of alcohol consumption in the prior 24 h.
Julianne D. Jett, Mohammad Keshtkar, Emma Seidler, Katharine Palmer, Diana Tyutyunnyk, Rachael Beck, Sara C. Parent, Douglas L. Weeks, Naomi Chaytor, Sterling M. McPherson, Michael G. McDonell   +10 more
wiley   +1 more source

DSM-5 full syndrome, other specified, and unspecified eating disorders in Australian adolescents: prevalence and clinical significance

, 2019
Background: Little information is available on the prevalence of Diagnostic and Statistical Manual of Mental Disorders (DSM)-5 eating disorders in adolescence, and eating disorders remain unique in the DSM for not systematically including a criterion ...
Bussey, K (15681077), Trompeter, N (15681074), Griffiths, S (15603782), Mitchison, D (15638924), Pike, KM (15685595), Hay, P (15527483), Jon Mond (14744557), Lonergan, A (15681080), Murray, SB (15638537)   +8 more
core  

Feeling Better Before, Not After: An Ecological Momentary Assessment of Affect Around Exercise in Women With Eating Disorders

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Maladaptive exercise includes excessive, compulsive, or compensatory exercise and is a common eating‐disorder (ED) symptom associated with increased severity, slower rates‐of‐recovery, and faster rates‐of‐relapse. Affect‐regulation theories posit that maladaptive exercise functions to reduce high negative affect (NA), although ...
Danielle A. N. Chapa, Kelsie T. Forbush, Yiyang Chen, Courtney E. Costain, Samiya I. Rasheed   +4 more
wiley   +1 more source

Ecological Momentary Interventions in the Management of Eating Disorders and Obesity: A Systematic Review

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This systematic review evaluated the feasibility, efficacy, adherence, and methodological quality of ecological momentary intervention (EMI)–based treatments for individuals with diagnosed eating disorders (EDs) and/or obesity. Method Eight electronic databases were systematically searched from inception to January 2026.
Wenlu Mao, Ricarda Schmidt, Emily K. Presseller, Adrienne Juarascio, Anja Hilbert   +4 more
wiley   +1 more source

A strategic roadmap for the Diagnostic and Scientific Manual (DSM) of mental disorders. [PDF]

World Psychiatry
Oquendo MA, Alpert JE, Yousif L, Gogtay N, Clarke DE.   +4 more
europepmc   +1 more source

Therapist‐Guided Smartphone‐Based Aftercare for Inpatients With Severe Anorexia Nervosa (SMART‐AN): A Randomized Clinical Trial

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To evaluate the efficacy of a 16‐week therapist‐guided, smartphone‐based aftercare intervention as an add‐on to treatment as usual (TAU) following inpatient treatment for anorexia nervosa (AN). Method In this single‐center randomized clinical trial, 186 female inpatients with DSM‐5 AN (≥ 13 years; body mass index (BMI) ≥ 15.0 kg/m2 ...
Sandra Schlegl, Andreas Gerich, Yannik Terhorst, Christina Fricke Neumayr, Ulrich Voderholzer   +4 more
wiley   +1 more source

Longitudinal Residential Eating Disorder Treatment Outcomes for Binge‐Eating Disorder When Using the Unified Treatment Model

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Despite its prevalence, research on binge‐eating disorder (BED) outcomes for residential treatment remains limited. To address this research scarcity, we evaluated changes in ED behaviors and comorbid symptoms, including depression and anxiety, for patients with BED that received residential eating disorder (ED) care from a ...
Kiki M. Kline, Briana Delibashi, Gayle Brooks, Shelby N. Ortiz   +3 more
wiley   +1 more source

Structural Validity of a Short Form of the Eating Disorder Examination Questionnaire in Adolescents Diagnosed With an Eating Disorder

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study aimed to assess the structural validity and readability of a brief 7‐item version of the Eating Disorder Examination Questionnaire (the EDE‐Q7) among adolescents. Method Latent variable analysis was used in a sample of 263 adolescents (age range = 13–17.99y) diagnosed with an eating disorder and recruited from treatment ...
Paul E. Jenkins, Sasha Gorrell, Erin C. Accurso, Sarah Eckhardt, Elizabeth K. Hughes, Daniel Le Grange, Susan M. Sawyer, Renee D. Rienecke   +7 more
wiley   +1 more source

Low-Threshold Optical Bistability in Detuned DBR Heterostructures Integrated with Dirac Semimetals. [PDF]

Nanomaterials (Basel)
Wu Y, Hu J, Wu W, Wang Y.
europepmc   +1 more source