Results 71 to 80 of about 256,251 (278)

Influence of Body Mass Index on Survival and Prognosis in Squamous Cell Carcinoma of Head and Neck

open access: yesCancer Management and Research, 2020
Peng Li,1 Liyan Sun,2 Luyan Sun3 1Department of Head Neck and Thyroid Surgery, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, People’s Republic of China; 2Department of Orthodontics, SATH Hospital of Stomatology, Henan University ...
Li P, Sun L, Sun L
doaj  

Model construction for decision support systems for beef stations [PDF]

open access: yes, 1990
Decision Support System (DSS)
Anderson, B.
core  

Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism

open access: yesAdvanced Science, EarlyView.
Fluorinated carnitines, fluoromethyl carnitine (FMC) and [18F]fluoromethyl carnitine ([18F]FMC), are synthesised and established as powerful probes to interrogate carnitine biology. The multimodal detection facilitated by fluorine labelling, including 19F NMR, mass spectrometry, and positron emission tomography imaging, allowed for visualisation of ...
Richard S. Edwards   +8 more
wiley   +1 more source

Decision Support System for Selecting Village Fund BLT Recipients using ROC and WASPAS Methods

open access: yesSistemasi: Jurnal Sistem Informasi
The Village Fund Direct Cash Assistance (BLT) Program is a government initiative aimed at improving social welfare, reducing inequality, and supporting economically disadvantaged communities.
Marisah Elfrida Manurung   +3 more
doaj   +1 more source

NPM1 Mediates mRNA Sorting into Extracellular Vesicles via Specific RNA Motif Binding and Phase Separation

open access: yesAdvanced Science, EarlyView.
NPM1 selectively sorts specific mRNAs into extracellular vesicles (EVs) by recognizing RNA motifs and forming phase‐separated condensates. These mRNA cargos—including EGFR—are then loaded via multivesicular bodies. This active sorting pathway, validated in EVs derived from both lung cancer cells and patient serum, reveals a specific mechanism for ...
Kaixiang Zhang   +8 more
wiley   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu   +6 more
wiley   +1 more source

High-rate self-synchronizing codes [PDF]

open access: yes, 2012
Self-synchronization under the presence of additive noise can be achieved by allocating a certain number of bits of each codeword as markers for synchronization.
Fujiwara, Yuichiro, Tonchev, Vladimir D.
core   +1 more source

Resolvin D5 Inhibits CXCL8 Expression in Colonic Epithelial Cells Through Activating GPR101 to Impede Neutrophil Recruitment and Consequently Alleviate Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
RvD5 effectively alleviates UC by inhibiting STAT1 signaling to reduce CXCL8 expression in colonic epithelial cells via activation of GPR101, which subsequently decreases the infiltration of neutrophils in the colonic mucosal epithelium. Epimedin A1, a natural allosteric inhibitor of 5‐LOX, demonstrates potential as a therapeutic agent for UC by ...
Pengxiang Guo   +9 more
wiley   +1 more source

How Incorporating Feedback Mechanisms in a DSS Affects DSS Evaluations

open access: yesInformation Systems Research, 2009
Model-based decision support systems (DSS) improve performance in many contexts that are data-rich, uncertain, and require repetitive decisions. But such DSS are often not designed to help users understand and internalize the underlying factors driving DSS recommendations.
Kayande, Ujwal   +4 more
openaire   +2 more sources

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao   +11 more
wiley   +1 more source

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