Results 121 to 130 of about 138,619 (284)

Projected Warming of the Southern Ocean Disrupts Embryonic Development and Hatch Timing in Antarctic Fish

Global Change Biology Communications, EarlyView.
Embryos are particularly sensitive to thermal challenge. Antarctic fish embryos raised at projected Southern Ocean temperatures hatch during the winter, have a high incidence of morphological abnormalities, have shorter body lengths, and express genes indicative of cellular stress.
Margaret Streeter, Nathalie R. Le François, Thomas Desvignes, Jacob Grondin, John H. Postlethwait, H. William Detrich III, Jacob M. Daane   +6 more
wiley   +1 more source

P36 CATHEPSIN-S INHIBITION HAS A DUAL THERAPEUTIC EFFECT ON THE SYSTEMIC AND PERIPHERAL PATHOMECHANISMS OF LUPUS NEPHRITIS

Kidney International Reports, 2016
S. Kumar VR, M. Tato, Y. Liu, S. Mulay R, S. Gruner, W. Haap, G. Hartmann, H.J. Anders   +7 more
doaj   +1 more source

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

Journal of Applied Toxicology, EarlyView.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu, Bing Liu, Keli Wang, Xiaoyu Wang, Zhen Sun, Xiaojuan Pan, Zengming Zhao   +6 more
wiley   +1 more source

Transforming healthcare with large language models: Current applications, challenges, and future directions—a literature review

Journal of Intelligent Medicine, EarlyView.
Abstract AI‐based large language models (LLMs) have gradually made their way into various fields, transforming industries and changing the way we solve problems. LLMs have great potential in healthcare, where they can share the burden of data management, retrieval, and decision‐making.
Muhammad Umar, Vanessa Ali, Laiba Shamim, Imshaal Musharaf, Rabia Hafsa, Muhammad Umar Ahsan, Osama Ahmad, Lamea Bint Sabhan, Muhammad Saeed, Somaiya Ahmed, Sana Iftikhar, Noor Ul Ain   +11 more
wiley   +1 more source

Microstructural, physicochemical, thermal, and rheological properties of starches from commonly consumed yam varieties in West Africa

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND This study assessed the starch content of ten yam varieties commonly consumed in West Africa to clarify their structural, thermal, physicochemical, and rheological properties and to support their potential food and industrial applications.
Patrick Olusanmi Adebola, Paterne Agre, Asrat Asfaw, Amani Michel Kouakou, Alexandre Dansi, Jude Obidiegwu, Emmanuel Chamba, Nkosingiphile L. Nzama, Toluwase A. Dada, Eric Oscar Amonsou   +9 more
wiley   +1 more source

A comprehensive review of the recent advances on predicting drug-target affinity based on deep learning

Frontiers in Pharmacology
Accurate calculation of drug-target affinity (DTA) is crucial for various applications in the pharmaceutical industry, including drug screening, design, and repurposing.
Xin Zeng, Shu-Juan Li, Shuang-Qing Lv, Meng-Liang Wen, Yi Li   +4 more
doaj   +1 more source

A subset of ipRGCs regulates both maturation of the circadian clock and segregation of retinogeniculate projections in mice [PDF]

, 2017
et al,, Gray, Paul A, Herzog, Erik D, VanDrunk, Cassandra   +3 more
core   +2 more sources

Catalyst‐Free Mass Polymerization and Characterization of Bio‐Polyhydroxhyurethanes Based on Resorcinol Bis(Cyclocarbonate)

Macromolecular Materials and Engineering, EarlyView.
Non‐isocyanate polyhydroxyurethanes (PHUs) were synthesized from resorcinol bis(cyclocarbonate) and eco‐friendly diamines under mild, catalyst‐free conditions. The resulting polymers were extensively characterized for their structural, thermal, and mechanical properties, as well as processability and adhesion performance.
Federico Olivieri, Noemi Faggio, Giovanni Dal Poggetto, Chiara Santillo, Roberto Avolio, Rachele Castaldo, Mariacristina Cocca, Maria Emanuela Errico, Marino Lavorgna, Gennaro Gentile   +9 more
wiley   +1 more source

Molecular characterization of Methicillin-resistant Staphylococcus aureus isolated in ready-to-eat food sold in supermarkets in Bobo-Dioulasso: case of charcuterie products

BMC Infectious Diseases
Background Staphylococcus aureus (S. aureus) is one of the most widespread bacterial pathogens in animals and humans, and its role as an important causative agent of food poisoning is well-documented.
Namwin Siourimè Somda, Alima Mah Esther Traoré, Domonbabele François de Sales Hien, Yemah Bockarie, Abel Tankoano, Donatien Kaboré, Ouindgueta Juste Isidore Bonkoungou, Hagrétou Sawadogo-Lingani, Aly Savadogo   +8 more
doaj   +1 more source

Comparing the power of phylogenetic, trait and network structure information to predict plant–frugivore interactions

Oikos, EarlyView.
Due to the constraints of limited effort and sampling error, observed species interaction networks are an imperfect representation of the ‘true' underlying community. Link prediction methods allow us to construct a potentially more complete representation of a given empirical network by guiding targeted sampling of predicted links, as well as offer ...
Grant Foster, Tad A. Dallas
wiley   +1 more source