Results 91 to 100 of about 18,732 (256)

New biosensors and transgenic mice for multiplex cGMP imaging

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a versatile second messenger that is important for human (patho‐)physiology and pharmacotherapy. Live‐cell imaging of cGMP with biosensors allows to elucidate its spatiotemporal dynamics in real time under close‐to‐native conditions. However, to monitor two separate cGMP pools or cGMP/cAMP
Markus Wolters, Martin Thunemann, Barbara Birk, Susanne Feil, Viacheslav O. Nikolaev, Moritz Lehners, Robert Feil   +6 more
wiley   +1 more source

Investigation of the reactions of chlorides binding to aluminates using XRD and DTA methods

Hemijska industrija, 2009
The reactions of chlorides binding to aluminates were investigated by analyzing the monochloroaluminate hydrate, product of the reaction. The results show that the product is formed in the fresh concrete, after adding chloride within the stage of the preparation of concrete, as well as adding chlorides by penetration from the environment into the ...
openaire   +3 more sources

Artificial intelligence for detection and segmentation of accessory root canals in endodontic imaging: A systematic review

European Journal of Oral Sciences, EarlyView.
Abstract Accessory root canal anatomy, including second mesiobuccal (MB2) and middle mesial canals (MMC), is difficult to identify and may compromise endodontic outcomes when missed, supporting artificial intelligence (AI)‐based diagnostic tools. This systematic review (CRD420261415943) included studies evaluating AI models for accessory canal or root ...
Hugo Henrique dos Santos Dantas Guimarães, Karla Nogueira Matos   +1 more
wiley   +1 more source

Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism

The FEBS Journal, EarlyView.
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney, James Griffin, Nouf Khan, Balnur Ibrash, Matthew J. O'Connor, Tomas Venit, Elizabeth Mayela Ambrosio, Spiros A. Pergantis, Elke Ober, Piergiorgio Percipalle, Kirsten C. Sadler   +10 more
wiley   +1 more source

Deep Learning Models for Detection of Periapical Radiolucent Lesions on Panoramic Radiographs: A Systematic Review and Meta‐Analysis

International Endodontic Journal, EarlyView.
ABSTRACT Background Panoramic radiographs are used routinely to screen dental conditions and treatment patterns. Recently, numerous studies have suggested that deep learning (DL) models can be utilized for analysing panoramic radiographs. Objective This review aimed to evaluate the accuracy of DL models in detecting periapical radiolucent lesions (PRLs)
Ibrahim Ali Ahmad, Raidan Ba‐Hattab, Sadeq Ali Al‐Maweri, Faleh Tamimi   +3 more
wiley   +1 more source

Deep Learning for Assessing Caries Depth in Permanent Teeth Using Intraoral Radiographs: A Systematic Review

International Endodontic Journal, EarlyView.
ABSTRACT Background Accurate assessment of caries depth on intraoral radiographs is crucial for determining the extent of the lesion and planning appropriate treatment. Artificial intelligence (AI) models have been increasingly used for detecting and classifying carious lesions; however, the evidence focusing specifically on the classification of ...
Laith Abu Qdais, Richard Gault, Jamie Toole, Aysar Khudair, Omer Butt, Ikhlas El‐Karim   +5 more
wiley   +1 more source

Clonal Hematopoiesis and CAR T Cell Therapy: From Biological Crosstalk to Clinical Implications

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Clonal hematopoiesis (CH) is increasingly recognized as a significant biological phenomenon in aging and cancer, marked by the expansion of hematopoietic stem and progenitor cells harboring somatic mutations in genes associated with myeloid neoplasms.
Wei Du, Shunsuke Koga, Guang Yang, Saar Gill, Adam Bagg   +4 more
wiley   +1 more source

How to Demonstrate Trustworthy Use of AI in Public Services: A Case Study

Information Systems Journal, EarlyView.
ABSTRACT Government leaders across the globe are grappling with how to harness and integrate artificial intelligence (AI) to enhance public service delivery and efficiency. Yet, a key challenge faced is how to build and maintain the trust of stakeholders. Trust is critical for the acceptance and sustained adoption of AI technologies, as well as to gain
Natalie Smith, Nicole Gillespie, Tapani Rinta‐Kahila, Steven Lockey, Javad Pool, Caitlin Curtis   +5 more
wiley   +1 more source

Improving Digital Transformation Outcomes and Pace: The Role of the Board and C‐Suite in Reducing Transformation Friction

Information Systems Journal, EarlyView.
ABSTRACT Most organisations are confronting a dilemma: the need to embark on digital transformation to be competitive and sustainable versus the inherently high costs and extremely high risks involved. Lack of executive support has long been identified as a leading cause of project failure, including digital transformation projects.
Natalie Smith, Andrew Burton‐Jones
wiley   +1 more source

Climate‐Neutrality Transition and Banks' Loan Pricing

Journal of Financial Research, EarlyView.
Abstract In this paper, we propose a novel methodology to quantify firms' climate‐change transition risk (CCTR) and its implications for credit markets. We utilize the regulatory framework of the European Green Deal's 2050 carbon neutrality roadmap, focusing on large Eurozone firms and their banking relationships.
Evangelos Salachas, Maria‐Eleni K. Agoraki, Georgios P. Kouretas   +2 more
wiley   +1 more source