Results 101 to 110 of about 40,757 (198)
ABSTRACT Background Respiratory motion artifacts impair diagnostic accuracy in gadoxetic acid disodium (Gd‐EOB‐DTPA)‐enhanced liver MRI. Conventional verbal pre‐scan breathing training often yields inconsistent patient cooperation and image quality, creating an urgent clinical need for optimized training methods.
Li Mei +7 more
wiley +1 more source
ABSTRACT Purpose To determine the feasibility of measuring brain clearance of gadolinium contrast agent using standard intravenous DCE‐MRI acquisitions and evaluate the contribution of blood–brain barrier (BBB) and non‐BBB clearance routes. Methods Uptake and extended Tofts models were fit to DCE‐MRI data from people with Parkinson's disease, post ...
Martin Kozár +8 more
wiley +1 more source
Using Manganese‐Enhanced DCE‐MRI to Assess Blood‐Cerebrospinal Fluid Barrier Transport
ABSTRACT PurposeWe developed a dynamic, heavily T2‐weighted (hT2w) FLAIR protocol to resolve acute Mn2+ transport kinetics, as a proxy for Ca2+, across the choroid plexus (ChP)—cerebrospinal fluid (CSF) interface, in vivo. By quantifying intercompartmental Mn2+ dynamics, and comparing these with Gd‐DOTA, we sought to characterize blood‐CSF‐barrier ...
Charith Perera +9 more
wiley +1 more source
EGF-receptors (EGFR) are overexpressed in gliomas, as well as in tumors of breast, lung, and urinary bladder. For this reason, EGFR may be an attractive target for both visualization and therapy of malignant tumors using radioactive nuclides.
Carlsson, Jörgen, +5 more
core +1 more source
This schematic illustrates an L‐NAME‐induced preeclampsia (PE) rat model generated via L‐NAME administration to pregnant dams, wherein Morris water maze assessments confirmed progressive postpartum cognitive dysfunction that emerged at 10 days post‐partum and deteriorated further at 1 and 3 months post‐partum. Multimodal magnetic resonance imaging (MRI)
Yong Xia, Junguo Zhao, Bo Gao
wiley +1 more source
Biokinetic Modelling of DTPA Decorporation Therapy: the CONRAD Approach
Administration of diethylene triamine pentaacetic acid (DTPA) can enhance the urinary excretion rate of plutonium (Pu) for several days, but most of this Pu decorporation occurs on the first day after treatment.
Luciani, A.
core +3 more sources
On the measurement of glomerular filtration rate: An odyssey into the milieu intérieur
Experimental Physiology, EarlyView.
Anders Møller Greve +4 more
wiley +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Advances in Peptide‐Targeted Fluorescent Probes for the Diagnosis and Therapy of Brain Disorders
This review summarizes peptide‐based fluorescent probes for major brain diseases, such as Alzheimer's and Parkinson's. It highlights their precise biomarker targeting and high sensitivity for imaging pathological processes in vivo. These probes also show great potential for enabling theranostic applications, thereby offering real‐time monitoring and ...
Shuangjing Yang +4 more
wiley +1 more source
RATIONALE AND OBJECTIVES. TO compare the magnetic resonance (MR) imaging characteristics of gadolinium-DTPA (Gd-DTPA), a low-molecular-weight contrast agent, and polylysine-Gd-DTPA, a macromolecular contrast agent, in two types of hepatocarcinomas (HCC ...
Mottet, I. +5 more
core +1 more source

