Results 111 to 120 of about 65,455 (240)

Impact of Frequent Immune‐Mediated Adverse Events on Treatment Continuity and Outcomes During Durvalumab Plus Tremelimumab Therapy for Unresectable Hepatocellular Carcinoma

Liver International Communications, Volume 7, Issue 2, June 2026.
ABSTRACT Durvalumab plus tremelimumab (Dur/Tre) is the first‐line treatment for unresectable hepatocellular carcinoma (uHCC). Immune‐mediated adverse events (imAEs) are common; however, the impact of specific imAE types on treatment persistence and outcomes remains unclear.
Tomomitsu Matono, Toshifumi Tada, Atsushi Hiraoka, Masashi Hirooka, Kazuya Kariyama, Joji Tani, Masanori Atsukawa, Koichi Takaguchi, Ei Itobayashi, Shinya Fukunishi, Kunihiko Tsuji, Toru Ishikawa, Kazuto Tajiri, Hironori Tanaka, Hidenori Toyoda, Chikara Ogawa, Takashi Nishimura, Takeshi Hatanaka, Satoru Kakizaki, Kazuhito Kawata, Atsushi Naganuma, Hisashi Kosaka, Hidekatsu Kuroda, Yutaka Yata, Hiroki Nishikawa, Michitaka Imai, Tomoko Aoki, Hironori Ochi, Hideyuki Tamai, Shohei Komatsu, Hideko Ohama, Fujimasa Tada, Shinichiro Nakamura, Kazuhiro Nouso, Asahiro Morishita, Norio Itokawa, Tomomi Okubo, Taeang Arai, Akemi Tsutsui, Takuya Nagano, Kazunari Tanaka, Takanori Matsuura, Yoshihide Ueda, Yuichi Koshiyama, Yuki Kanayama, Hidenao Noritake, Hirayuki Enomoto, Kosuke Matsui, Masaki Kaibori, Takumi Fukumoto, Yoichi Hiasa, Masatoshi Kudo, Takashi Kumada, on behalf of the RELPEC Group and HCC 48 Group   +53 more
wiley   +1 more source

Growing Australian Rice in Non‐Flooded Soil Increases Water Use Efficiency and Mycorrhizal Colonisation, but Reduces Grain Micronutrient Concentrations

Journal of Sustainable Agriculture and Environment, Volume 5, Issue 2, June 2026.
ABSTRACT Climate change is driving a global shift from flooded (anaerobic) to dryland/rainfed (aerobic) rice production. While aerobic systems reduce water use and methane emissions, they can exacerbate soil zinc (Zn) and iron (Fe) deficiencies due to altered redox conditions.
Thi Diem Nguyen, Nathaniel Jewell, Chris Brien, Bettina Berger, Alexander A. T. Johnson, Stephanie J. Watts‐Williams   +5 more
wiley   +1 more source

Synthesis of Gd-dtpa-folat for Magnetic Resonance Imaging Contrast Agent and Characterization by Using 153gd-dtpa-folate Radioactive [PDF]

, 2012
Contrast agent was used to clarify the image of the organ that is difficult to distinguish by MRI (Magnetic Resonance Imaging) techniques, particularly in soft tissues of the central nervous system, liver, digestive system, lymphatic system, breast ...
G, A. H. (Adang), Maskur, M. (Maskur), S, Y. (Yono)   +2 more
core  

The Effect of Summer Cover Cropping on Soil Health Is Limited by the Quantity of Carbon Inputs in a Winter Dominant Low Rainfall Environment

Journal of Sustainable Agriculture and Environment, Volume 5, Issue 2, June 2026.
ABSTRACT The effects of summer cover crops on cash crop yields and soil health in semi‐arid cropping systems in southern Australia remain largely unexplored. A study was conducted in Western Australia to investigate cover crop impacts on soil carbon and nitrogen cycling, soil water, and mineral nitrogen (N) and cash crop yield.
Abraham J. Gibson, Lee J. Kearney, Evanna McGuinness, Tina Astbury, Mick T. Rose, Terry J. Rose   +5 more
wiley   +1 more source

Atmospheric dust is a global nutrient source for plants via foliar uptake

New Phytologist, Volume 250, Issue 5, Page 2867-2883, June 2026.
Summary Atmospheric mineral dust is a critical nutrient supplier to marine ecosystems, but its role in terrestrial plant nutrition remains underexplored due to the assumption that nutrients are acquired solely from soils via roots. Here, we demonstrate that plants directly acquire nutrients from dust through leaves, revealing an unrecognized ...
Anton Lokshin, Daniel Palchan, Marcelo Sternberg, Tom Goren, Mahdi (André) Nakhavali, Avner Gross   +5 more
wiley   +1 more source

Interstitial lung disease in Malta [PDF]

, 2012
Aim: To establish the prevalence, management and response to treatment of interstitial lung disease (ILD) in Malta. Methodology: The personal files of 102 living and 26 deceased patients with ILD under the care of 4 respiratory physicians were reviewed ...
Fenech, Manwel, Gouder, Caroline, Montefort, Stephen   +2 more
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, Volume 20, Issue 5, Page 1202-1219, May 2026.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Differentiation of Fat‐Poor Renal Angiomyolipoma From Clear Cell Renal Cell Carcinoma: Diagnostic Performance of a Novel Type of Color Contrast Enhanced Ultrasound

Cancer Medicine, Volume 15, Issue 5, May 2026.
Our study confirms CPI can distinguish AML.wovf from ccRCC, potentially helping patients with AML.wovf avoid unnecessary surgery. These findings expand CPI's clinical utility, providing a promising tool for diagnosing renal tumors. ABSTRACT Background The similar imaging characteristics of renal angiomyolipoma without visible fat (RAML.wvf) and clear ...
Yiman Du, Xuyang Wang, Bo Jiang, Luda Song, Yukun Luo, Qiuyang Li   +5 more
wiley   +1 more source

Arbuscular mycorrhizal fungal inoculation increases the bioavailability of zinc and iron in wheat grain

PLANTS, PEOPLE, PLANET, Volume 8, Issue 3, Page 924-936, May 2026.
Bread wheat is an important crop that supplies calories and nutrients to the global population. Enhancing the concentrations and bioavailability of essential micronutrients in wheat is crucial for human nutrition, and we investigated whether arbuscular mycorrhizal (AM) fungi can contribute to the biofortification of wheat.
Thi Diem Nguyen, Alexander A. T. Johnson, Enzo Lombi, Casey L. Doolette, Euan Smith, Stephanie J. Watts‐Williams   +5 more
wiley   +1 more source

On the measurement of glomerular filtration rate: An odyssey into the milieu intérieur

Experimental Physiology, EarlyView.
Anders Møller Greve, Anna Agnes Lytzen, Hrefna Sæunn Einarsdóttir, Michael Perch, Ronan M. G. Berg   +4 more
wiley   +1 more source