Results 41 to 50 of about 66,167 (224)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Alterations in T1 of normal and reperfused infarcted myocardium after Gd-BOPTA versus GD-DTPA on inversion recovery EPI. [PDF]
, 1997 This study tested whether Gd-BOPTA/Dimeg or Gd-DTPA exerts greater relaxation enhancement for blood and reperfused infarcted myocardium. Relaxivity of Gd-BOPTA is increased by weak binding to serum albumin.
Cavagna, F +6 more
core
Root uptake of lipophilic zinc-rhamnolipid complexes [PDF]
, 2008 This study investigated the formation and plant uptake of lipophilic metal-rhamnolipid complexes. Monorhamnosyl and dirhamnosyl rhamnolipids formed lipophilic complexes with copper (Cu), manganese (Mn), and zinc (Zn). Rhamnolipids significantly increased
Hettiarachchi, Ganga M. +5 more
core +1 more source
Scientific Reports, 2017 The conventional chemotherapeutics could not be traced in vivo and provide timely feedback on the clinical effectiveness of drugs. In this study, poly(L-γ-glutamyl-glutamine)-paclitaxel (PGG-PTX), as a model polymer, was chemically conjugated with Gd ...
Lipeng Gao +13 more
doaj +1 more source
Preparation and Preliminary Biological Evaluation of 177Lu Labelled Rituximab
Journal of Isotopes, 2014 For evaluating whether 177Lu-Rituximab could be applied for radioimmunoimaging and radioimmunotherrapy of non-Hodgkin’s Lymphoma， Rituximab, a specific chimeric monoclonal antibody used in CD20-positive B-cell Non-Hodgkin’s Lymphoma, was conjugated to ...
MA Xiu-feng1;ZHANG Jun-li2;LI Hong-yu1,2;LIANG Ji-xin1;YANG Yun2;YANG Chun-hui2;DU Jin1,3
doaj +1 more source
Alchemy, 2020 Gadolinium merupakan salah satu golongan unsur tanah jarang yang menarik karena memiliki sifat paramagnetik yang tinggi. Pengkhelatan gadolinium dengan ligan dietilentriaminpentaasetat (DTPA) menghasilkan senyawa yang berguna dalam bidang kesehatan ...
Santhy Wyantuti +3 more
doaj +1 more source
Engineered Graphene Quantum Dots as a Magnetic Resonance Signal Amplifier for Biomedical Imaging
Molecules, 2023 The application of magnetic resonance imaging (MRI) nano-contrast agents (nano-CAs) has increasingly attracted scholarly interest owing to their size, surface chemistry, and stability.
Zhongtao Li +5 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang +13 more
wiley +1 more source
Optimization of Reaction Conditions in the Production of Gadolinium Diethylenetriamine Pentaacetate-Folate [PDF]
, 2015 A previous study has performed the laboratory-scale synthesis and characterization of Gadolinium Diethylenetriaminepentaacetate-Folate. Some parameters associated with the synthesis have been defined.
Anggraeni, A. +3 more
core
Noninvasive monitoring of radiotherapy-induced microvascular changes using dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) in a colorectal tumor model [PDF]
, 2006 To examine dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) with a macromolecular contrast agent (P792) to visualize effects of radiotherapy (RT) on microvascular leakage in a colorectal cancer model.Journal Articleinfo:eu-repo/semantics ...
Backes, Walter +9 more
core +1 more source