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Synthesis and metal complexation properties of Ph-DTPA and Ph-TTHA: novel radionuclide chelating agents for use in nuclear medicine

Organic & Biomolecular Chemistry, 2005
We wish to report the synthesis and metal complexation properties of new radionuclide chelating agents for use in nuclear medicine. The strategy includes the facile preparation of rigid analogues of DTPA and TTHA possessing an aromatic ring. The aromatic structure used increased the stability of the complexes formed (pre-organization concept) and they ...
Gouin, Sébastien   +5 more
openaire   +3 more sources

On the reaction of dioxouranium(VI) with diethylene triaminepentaacetic acid (DTPA) and with chromium(III)-DTPA chelating agent

1998
Formation of complexes by dioxouranium(VI) with chromium(III)DTPA as "chelating agent" has been investigated, by potentiometry, in aqueous solution. Two chelates, a monomer and a dimer, with the same 1:1 dioxouranium(VI)/chromium(III)-DTPA molar ratio have been evidenced.
BUCCI, Remo   +3 more
openaire   +1 more source

Synthesis and Physicochemical Characterization of a New Gadolinium Chelate:  The Liver-Specific Magnetic Resonance Imaging Contrast Agent Gd-EOB-DTPA

Inorganic Chemistry, 1999
A convenient synthesis of disodium S-[4-(4-ethoxybenzyl)-3,6,9-tris[(carboxy-kappaO)methyl]-3,6,9-triazaundecandioato)(5-)-kappa(3)N(3)(),N(6)(),N(9)(),kappa(2)O(1)(),O(11)()]gadolinate(2-) (Gd-EOB-DTPA), 1, is reported. This water-soluble complex is presently undergoing phase III clinical trials as a liver-specific contrast agent for magnetic ...
H., Schmitt-Willich   +8 more
openaire   +2 more sources

[Metabolism and toxicity of therapeutic chelating agents. 14. Effect of DTPA on hematopoiesis].

Strahlentherapie, 1975
By use of 3-H-thymidine it is shown that toxic doses of Ca-DTPA lead to a reversible inhibition of DNA-synthesis in the lymphocytes, erythro- and myelopoietic cells of the rat. The incorporation of 59-Fe into the erythrocytes is markedly imparied. The hematological reaction, i. e.
openaire   +1 more source

Effect of soil ph and chelating agent (DTPA) on uptake by and distribution of 241am in plant parts of bush beans

Radiation Botany, 1972
Wallace A. Effect of soil pH and chelating agent (DTPA) on uptake by and distribution of 241 Am in plant parts of bush beans . Radiation Botany 12 , 433–435, 1972.—Bush bean ( Phaseolus vulgaris L. var. Improved Tendergreen) plants were grown with and without the chelating agent diethylenetriaminepentaacetate (DTPA) in Yolo loam soil which had ...
openaire   +1 more source

The Influence of Chelating Agents on the Kinetics of Calcite Dissolution

Journal of Colloid and Interface Science, 1998
H S Fogler
exaly  

Toward a Complete Removal of Barite (Barium Sulfate BaSO4\hbox {BaSO}_{4}) Scale Using Chelating Agents and Catalysts

Arabian Journal for Science and Engineering, 2017
Reyad A Shawabkeh   +2 more
exaly  

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