Results 1 to 10 of about 440,036 (332)

Prevalence, Clinical Characteristics, and Predictors of Difficult-to-Treat Inflammatory Bowel Disease in a Real-World Taiwanese Cohort [PDF]

open access: yesLife
A subset of patients with inflammatory bowel disease (IBD) remains refractory to treatment despite multiple lines of advanced therapies. These patients are often categorized as having difficult-to-treat (DTT) IBD. We retrospectively analyzed 354 patients
Shun-Wen Hsiao   +4 more
doaj   +2 more sources

Toxicity of Dithiothreitol (DTT) to Drosophila melanogaster

open access: yesToxicology Reports, 2021
The thiol-containing compound Dithiothreitol (DTT) has been shown to be toxic to cultured cells by inducing the generation of reactive oxygen species that ultimately cause cell death.
Yiwen Wang   +5 more
doaj   +3 more sources

Direct-to-treatment MRI-guided prostate radiotherapy using a generic patient-agnostic reference plan [PDF]

open access: yesTechnical Innovations & Patient Support in Radiation Oncology
Background:: Background and Purpose: Offline plan preparation is a time-consuming step in MRI-guided radiotherapy (MRIgRT). This work explores the use of a patient-agnostic reference plan and delineations for direct-to-treatment (DtT) MRI-guided prostate
Georgios Tsekas   +5 more
doaj   +2 more sources

High performance liquid chromatographic analysis of reduction products of a thiolated DNA for immobilization on gold nanoparticles [PDF]

open access: yesJournal of Nanostructures, 2019
DNA-based nano-biosensors are emerging scope in the field of biosensors. Many synthetic single stranded functional DNAs have been applied for development of such sensors, recently.
Fatemeh Javadi-Zarnaghi   +1 more
doaj   +1 more source

Superinfection with Difficult-to-Treat Pathogens Significantly Reduces the Outcome of Periprosthetic Joint Infections

open access: yesAntibiotics, 2021
Periprosthetic joint infection (PJI) is a serious complication after total joint arthroplasty. In the course of a PJI, superinfections with pathogens that do not match the primary infecting micro-organism may occur.
Ali Darwich   +7 more
doaj   +1 more source

Contribution of Physical and Chemical Properties to Dithiothreitol-Measured Oxidative Potentials of Atmospheric Aerosol Particles at Urban and Rural Sites in Japan

open access: yesAtmosphere, 2022
Dithiothreitol-measured oxidative potential (OPDTT) can chemically quantify the adverse health effects of atmospheric aerosols. Some chemical species are characterized with DTT activities, and the particle diameter and surface area control DTT ...
Kazuki Kurihara   +6 more
doaj   +1 more source

Pengaruh Pengetahuan Terhadap TV Digital Terestrial (DTT) dan Penggunaan Media terhadap Minat dalam Membeli Perangkat Penerima Siaran DTT

open access: yesBuletin Pos dan Telekomunikasi: Media Komunikasi Ilmiah, 2021
Penelitian ini bertujuan untuk mengetahui pengaruh antara pengetahuan terhadap digital terrestrial television (DTT) dan penggunaan media terhadap minat dalam menggunakan perangkat penerima DTT.
Diah Yuniarti, Sri Ariyanti
doaj   +1 more source

Dithiothreitol causes toxicity in C. elegans by modulating the methionine–homocysteine cycle

open access: yeseLife, 2022
The redox reagent dithiothreitol (DTT) causes stress in the endoplasmic reticulum (ER) by disrupting its oxidative protein folding environment, which results in the accumulation and misfolding of the newly synthesized proteins. DTT may potentially impact
Gokul G, Jogender Singh
doaj   +1 more source

The feasibility of distance to the tumor of biopsy cores to estimate the extracapsular extension

open access: yesProstate International, 2023
Background: To investigate the predictive capability of a new parameter, the distance between the fibromuscular capsule and the tumor as measured using a prostate biopsy core (referred to as “distance to the tumor” [DTT]), for the presence of ...
Chang Lim Hyun, Kyung Kgi Park
doaj   +1 more source

Recombinant Costimulatory Fusion Proteins as Functional Immunomodulators Enhance Antitumor Activity in Murine B16F10 Melanoma

open access: yesVaccines, 2020
Blocking inhibitory signaling and engaging stimulatory signaling have emerged as important therapeutic modalities for cancer immunotherapy. This study aimed to investigate immunomodulatory features of three recombinant costimulatory ligand proteins in a ...
Huaman Cai   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy