Results 131 to 140 of about 440,036 (332)

Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression

Advanced Science, EarlyView.
Mechanisms of Bufalin‐Mediated Intervention in Breast Cancer. ABSTRACT Breast cancer incidence is rising globally, presenting challenges such as treatment side effects and drug resistance. Bufalin is a bufadienolides compound with potential anti‐cancer effects. This study shows that bufalin inhibits malignant proliferation of MDA‐MB‐231 and MCF‐7 cells
Siyu Guo, Xiaodong Chen, Haojia Wang, Jiying Zhou, Peiying Lu, Jiangying Liu, Keyan Chai, Jingyuan Zhang, Siyun Yang, Shan Lu, Yifei Gao, Zhengsen Jin, Xiaoyu Tao, Zhongdong Hu, Qinglin Li, Jiarui Wu   +15 more
wiley   +1 more source

VALIDAÇÃO DO DITIOTREITOL (DTT) 0,04M: IMPACTO NA REDUÇÃO DO TEMPO DE ATENDIMENTO TRANSFUSIONAL EM PACIENTES TRATADOS COM DARATUMUMABE

Hematology, Transfusion and Cell Therapy
Objetivo: O Daratumumab (anti-CD38) é uma terapia bastante aplicada no tratamento de Mieloma Múltiplo (MM), porém o uso desse medicamento causa interferência nos exames de Imunohematologia devido a uma panaglutinação do soro do paciente com hemácias ...
HW Jesus, LD Santos, EP Bastos, MDG Messias, ALO Silva, MG Aravechia, CB Bub, JM Kutner   +7 more
doaj   +1 more source

Long-term storage protocol of reagent red blood cells treated with 0.01M dithiothreitol (DTT) for pre-transfusion testing of patients receiving anti-CD38 therapy, daratumumab

, 2023
Yuyuan Li, Chengyao Li, Ling Zhang, Jiao Li, Qixin Li, Haining Ouyang, Jiaona Luo, Lin-Rui Zhu, Kui Cai   +8 more
openalex   +1 more source

DTT interferometer and polarimeter systems

Journal of Instrumentation
Abstract Interferometers and polarimeters are commonly used in plasma experiments, particularly in magnetically confined fusion experiments, to measure plasma electron density and provide valuable insights on internal magnetic fields, respectively.
Donatella Fiorucci, Alessandro Fassina, Florian Dupin, Paolo Innocente, Davide Bonomi, Massimo Alonzo, Pierluigi Andreoli, Fabrizio Consoli, Andrea Doria, Francesco Filippi, Pasquale Gaudio, Michela Gelfusa, Leonardo Giudicotti, Valerio Piergotti, Giuliano Rocchi, Riccardo Rossi, Massimiliano Scisciò, David Terranova, Onofrio Tudisco   +18 more
openaire   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Gradient of microstructural damage along the dentato‐thalamo‐cortical tract in Friedreich ataxia

Annals of Clinical and Translational Neurology
Objective The dentato‐thalamo‐cortical tract (DTT) is the main cerebellar efferent pathway. Degeneration of the DTT is a core feature of Friedreich ataxia (FRDA).
Sirio Cocozza, Sara Bosticardo, Matteo Battocchio, Louise Corben, Martin Delatycki, Gary Egan, Nellie Georgiou‐Karistianis, Serena Monti, Giuseppe Palma, Chiara Pane, Francesco Saccà, Simona Schiavi, Louisa Selvadurai, Mario Tranfa, Alessandro Daducci, Arturo Brunetti, Ian H. Harding   +16 more
doaj   +1 more source

UMD Banach spaces and square functions associated with heat semigroups for Schr\"odinger and Laguerre operators

, 2012
In this paper we define square functions (also called Littlewood-Paley-Stein functions) associated with heat semigroups for Schr\"odinger and Laguerre operators acting on functions which take values in UMD Banach spaces.
Betancor, J. J., Castro, A. J., Fariña, J. C., Rodríguez-Mesa, L.   +3 more
core  

DTT: a divertor tokamak test facility for the study of the power exhaust issues in view of DEMO [PDF]

, 2016
R. Albanese
openalex   +1 more source

Astrocyte Enrichment of 3D Cortical Constructs Enhances Brain Repair

Advanced Science, EarlyView.
This study highlights the role of astrocytes in supporting neural progenitor cell survival and differentiation after traumatic brain injury. Astrocytes enhanced neuronal differentiation, improved cell survival in co‐cultures, and promoted integration of microfluidics‐based implants with host tissue following implantation. Additionally, increased axonal
Elisa M. Cruz, Luana C. Soares, Gretchen Greene, Fernando Messore, Mohammed Abuelem, Mingyu Li, Caroline Andersen, Mirriam Domocos, Elisa Vitiello, Rabeah Abdul Razak, Marlene Lawston, Gabriel Moser, Talia Vasaturo‐Kolodner, Mona Barkat, Roslyn M. Bill, Edward Mann, Linna Zhou, Mootaz M. Salman, Hagan Bayley, Zoltán Molnár, Francis G. Szele   +20 more
wiley   +1 more source

dtts: 'data.table' Time-Series [PDF]

, 2022
Dirk Eddelbuettel and Leonardo Silvestri
openalex   +1 more source