Results 141 to 150 of about 4,798,027 (263)

Diacerein Disrupts Testicular Homeostasis: The Essential Role of Basal Cytokines in Maintaining Sertoli Cell Integrity and the Immune Microenvironment

open access: yesAndrology, EarlyView.
ABSTRACT Background Pro‐inflammatory cytokines, TNF and IL‐1B, are essential for testicular homeostasis. Diacerein, an anti‐inflammatory drug, inhibits these cytokines, impairing M2 macrophages and Leydig cells (LCs). However, its impact on Sertoli cells (SCs) and M1 (CD68) macrophages remains unknown.
Elide Loise Freitas de Jesus   +6 more
wiley   +1 more source

Advances in 4D Representation: Geometry, Motion, and Interaction

open access: yesComputer Graphics Forum, EarlyView.
We survey 4D representation through three key pillars — geometry, motion, and interaction — offering a selective, representation‐centric perspective to guide researchers in choosing and customizing the right 4D representation for their tasks. Abstract We present a survey on 4D generation and reconstruction, a fast‐evolving subfield of computer graphics
M. Zhao   +7 more
wiley   +1 more source

Recent Trends in Inverse Rendering

open access: yesComputer Graphics Forum, EarlyView.
This survey reviews 84 papers published between 2020 and 2025 on inverse rendering methods, introducing a taxonomy based on input data, scene representations, optimization strategies, and evaluation methods. We analyze emerging trends in neural, differentiable, and Gaussian‐splatting approaches, discuss applications, and identify key challenges and ...
S. Ullah, F. Pellacini, A. Giachetti
wiley   +1 more source

Ammonia Accumulation Drives Intervertebral Disc Degeneration by Triggering Ammonia‐Induced Cell Death Through Lysosome–Mitochondria Crosstalk

open access: yesCell Proliferation, EarlyView.
Mechanical strain disrupts the lysosome‐mitochondria axis via GLS1‐mediated ammonia toxicity, causing NP cell death and ECM breakdown in IVDD. CB839‐mediated GLS1 inhibition effectively rescues cellular homeostasis and alleviates disc degeneration.
Yang Zhang   +11 more
wiley   +1 more source

A High-Power Dual-Transformer-Based Dual Active Bridge Converter Suitable for Electric Vehicles

open access: yes
Publisher Copyright: © 2023 IEEE.The necessity of incorporating a dual active bridge (DAB) converter in electric vehicles (EVs) has been widely recognized in recent years.
Babalou, Milad   +3 more
core   +1 more source

A Biweekly GLP‐1R Agonist Designed With Drug‐Free Intervals for Enhanced Efficacy, Receptor Homeostasis and Gastrointestinal Tolerability

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To develop a next‐generation, longer‐acting, more‐clinical‐benefits agonist to achieve sustained efficacy with improved tolerability. Methods CT130 was designed from semaglutide. Binding affinity was validated via molecular dynamics and cellular assays.
Wei Ding   +4 more
wiley   +1 more source

Research on control strategy of bidirectional energy storage converter for a certain type of export locomotive

open access: yes机车电传动
Dual active bridge (DAB) converters are widely used in DC microgrids, fuel cells, electric vehicles, and other fields, due to their advantages of high power density, bi-directional energy flow, electrical isolation, and the ease of soft switching ...
CHEN Zhe   +3 more
doaj  

The MacBrain Resource Center (MBRC) rhesus macaque embryonic brain histology datasets

open access: yesJournal of Anatomy, EarlyView.
We introduce the MacBrain Resource Center (MBRC) Collections of rhesus macaque embryonic brain tissue. Here, we illustrate histo‐ and immunohistology from our dynamically growing Collection 6, which currently contains >10,000 zoomable and downloadable images from n = 14 male and female embryos from early to late in gestation.
Valeria Mendoza‐Silva   +11 more
wiley   +1 more source

Multiplexed Nanosensors for Real‐Time Monitoring of VOC‐Mediated Signalling Response in Plants

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT To enhance crop performance, intercropping strategies leverage volatile organic compound (VOC)‐driven interactions with companion plants that constitutively emit VOCs. Despite the agricultural importance, the mechanisms and kinetics of VOC‐mediated sensory transduction in receiver plants eavesdropping on neighbouring non‐kin emitters remain ...
Mervin Chun‐Yi Ang   +13 more
wiley   +1 more source

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