Results 131 to 140 of about 12,402,633 (259)

Genetically Proxied GIP‐GIPR Pathway Perturbation and Fracture Risk

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To determine whether genetic proxies for incretin pathway perturbation are associated with fracture risk and bone mineral density, providing human genetic evidence relevant to the skeletal safety of incretin‐based therapies. Materials and Methods We conducted drug‐target Mendelian randomisation using cis genetic variants near GIP, GIPR ...
Wenjie Cheng, Weijie Liu, Jie Wei, Chao Zeng, Houchen Lyu, Sizheng Steven Zhao   +5 more
wiley   +1 more source

Weight Regain After Incretin Treatment: The Lean Mass Deficit Hypothesis and a Role for Testosterone Combination Therapy in Men

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs), dual glucose‐dependent insulinotropic polypeptide (GIP)/GLP‐1RA and triple (GIP)/GLP‐1RA/glucagon agonists achieve placebo‐subtracted weight loss of 15% to 22%. Their long‐term value depends on how well the weight loss is maintained and on the composition of weight loss, not only
Michael Zitzmann, Zsolt Bosnyak, Richard Jones, Monica Caliber   +3 more
wiley   +1 more source

Changes in Muscle Strength Following Semaglutide Treatment in Adults: A Systematic Review With Meta‐Analysis of Handgrip Strength

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To systematically review and quantitatively synthesize within‐group changes in skeletal muscle strength following semaglutide treatment in adults. Materials and Methods This PRISMA 2020 systematic review was registered in PROSPERO (CRD420251185935).
Luís Guilherme Machado, Pedro Henrique Siedschlag Schmidt, Guido Tasca Petroski, Geraldo Lucas Lopes Costa, Letícia Vieira dos Santos Ribeiro, João Victor Ramos Da Cruz, Graziela De Luca Canto, Alexandre Hohl, Marcelo Fernando Ronsoni, Simone van de Sande‐Lee   +9 more
wiley   +1 more source

Association Between Locomotive Syndrome and Metabolic Dysfunction‐Associated Steatotic Liver Disease in a Health Examination Cohort: A Cross‐Sectional Study

Hepatology Research, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) is associated with liver fat and other health problems. In this study of 7776 adults who underwent health examinations, early mobility impairment was more common in individuals with MASLD.
Shinya Yokoyama, Takanori Ito, Taku Tanaka, Hiroaki Hiraiwa, Takashi Honda, Yoji Ishizu, Norihiro Imai, Kenta Yamamoto, Kazuki Sahara, Tetsuhito Kojima, Naoyoshi Kariya, Hiroki Kawashima   +11 more
wiley   +1 more source

High‐Intensity Interval Training Modulates NLRP3 Inflammasome‐Related Expression and Monocyte Subset Distribution in Adults With Obesity: A Randomised Trial

Immunology, EarlyView.
In sedentary adults with obesity, 8 weeks of high‐intensity interval training prevented the shift toward a pro‐inflammatory monocyte profile seen in nontrained controls—most robustly, a significantly lower proportion of intermediate monocytes at Week 8 (p = 0.014) while the control group also showed a within‐group rise in NLRP3 expression not observed ...
Daniela A. de Abreu, Ana Luíza P. A. Silveira, Stella de S. Vieira, Francisco A. H. Fonseca, Maria Cristina Izar, Jônatas B. do Amaral, Carolina N. França   +6 more
wiley   +1 more source

Identification and Treatment of Anorexia Nervosa in Women With Perimenopause

Journal of Midwifery &Women's Health, EarlyView.
Abstract Disordered eating is a common problem that midwives will encounter as frontline primary care providers. Anorexia nervosa (AN) is a form of disordered eating that results in chronic starvation state, creating significant risk of morbidity and mortality to the patient. AN is traditionally considered a disorder of adolescence and young adulthood;
Janell Senda, Sarah Carpenter, Mary Carter‐Orbke   +2 more
wiley   +1 more source

European Consortium for Lipodystrophies consensus definition and classification framework for monogenic lipodystrophy

Journal of Internal Medicine, EarlyView.
Abstract Lipodystrophy comprises a heterogeneous group of disorders characterized by reduced adipose tissue often associated with severe metabolic complications. Lipodystrophy may be genetic, acquired, or secondary to medical therapies initiated for other conditions.
Robert K. Semple, Martin Wabitsch, Baris Akinci, Saif Alyaarubi, Marjoleine F. Broekema, Rebecca J. Brown, Giovanni Ceccarini, Carolina Cecchetti, Solaf M. Elsayed, Antía Fernández‐Pombo, Alessandra Gambineri, Ingrid M. Jazet, Lotte Kleinendorst, Konstanze Miehle, Elif A. Oral, Flavia Prodam, Ferruccio Santini, David B. Savage, Nadia Shaukat Ali, Ekaterina Sorkina, Magdalena Szopa, Marie‐Christine Vantyghem, Camille Vatier, Corinne Vigouroux, Julia von Schnurbein, David Araújo‐Vilar   +25 more
wiley   +1 more source

Do reductions in out-of-pocket expenses for dual energy X-ray absorptiometry scans translate to reduced fracture incidence amongst older Australians? A population-based study

, 2018
Do reductions in out-of-pocket expenses for dual energy X-ray absorptiometry scans translate to reduced fracture incidence amongst older Australians?
Amelia Betson (13058094), Julie Pasco (13077054), KL Holloway-Kew (14448492), Amanda Stuart (13059444), Sarah Hosking (13094556), Lana Williams (13082460), SL Brennan-Olsen (14446464)   +6 more
core  

Association Among Eating Speed, Dietary Diversity, and Fat‐Free Mass Index in Adults

Journal of Oral Rehabilitation, EarlyView.
This study examined the associations among body composition indices, eating speed, and dietary diversity. Dietary diversity was positively associated with muscle mass in men and negatively associated with body fat mass index in women, while fast eating was significantly associated with fat‐free mass index.
Takatoshi Hiroshimaya, Komei Iwai, Marika Marutani, Tetsuji Azuma, Takatoshi Yonenaga, Koichiro Tabata, Kazutoshi Watanabe, Michiya Ohno, Mitsuru Seishima, Takaaki Tomofuji, Naofumi Tamaki   +10 more
wiley   +1 more source

Metabolic Adaptations to Weight Loss in Obese Senior Dogs: Effects on Energy Expenditure, Protein Turnover, and Voluntary Physical Activity

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Implications of obesity and weight loss (WL) for energy and protein metabolism are not fully understood, particularly in senior dogs. This study evaluated changes in body composition, energy expenditure (EE), protein turnover (PT), and voluntary physical activity (VPA) in senior dogs in maintenance and after 10% and 20% WL.
Ticiane Giselle Bitencourt Freire, Jhennifer de Castro Fenerick, Ariel de Castro, Maria Eduarda Gonçalves Tozato, Stephanie de Souza Theodoro, Letícia Grazielle Pacheco, Camila Goloni, Caroline Paschoal, Vladimir Eliodoro Costa, Aulus Cavalieri Carciofi   +9 more
wiley   +1 more source