Results 81 to 90 of about 145,450 (382)

A Pharmacometric Method for Quantitative Determination of Improvement in Body Composition and Characterization of the Exposure–Response Relationship during Treatment of Obesity with Tirzepatide

Clinical Pharmacology &Therapeutics, EarlyView.
About half of the world's population is living with overweight or obesity. Tirzepatide is an approved treatment for chronic weight management. We sought to characterize the exposure–response relationship for weight reduction in patients with overweight or obesity and quantify the associated changes in body composition.
Emmanuel Chigutsa, Lucy Her, Xiaosu Ma, Shweta Urva, Karen Schneck   +4 more
wiley   +1 more source

Bone mineral density assessment for research purpose using dual energy X-ray absorptiometry

Osteoporosis and Sarcopenia, 2018
Dual energy X-ray absorptiometry (DXA) has become the most common method for measuring bone mineral density (BMD) of small animals in metabolic bone disease research, and errors should be minimized in all procedures involved in research studies in order ...
Ho Sung Kim, Eun Sun Jeong, Myung Hwa Yang, Seoung-Oh Yang   +3 more
doaj   +1 more source

Distinct blood volume and left ventricular adaptation to severe obesity in middle‐aged adults at risk for heart failure

European Journal of Heart Failure, EarlyView.
Obesity, blood volume and ventricular remodelling. BMI, body mass index; DEXA, dual‐energy X‐ray absorptiometry; IR, increased risk; LVEDV, left ventricular end‐diastolic volume; LVEDVi, left ventricular end‐diastolic volume index. Created in BioRender. Wakeham, D.
Joseph Campain, Denis J. Wakeham, Katrin Dias, James P. MacNamara, Mitchel Samels, Erin J Howden, Graeme Carrick‐Ranson, Michinari Hieda, Benjamin D. Levine, Satyam Sarma, Christopher M. Hearon Jr   +10 more
wiley   +1 more source

Concordance between muscle mass assessed by bioelectrical impedance analysis and by dual energy X-ray absorptiometry: a cross-sectional study

BMC Musculoskeletal Disorders, 2015
BackgroundBesides magnetic resonance imaging, dual energy X-ray absorptiometry (DXA) seems the most reliable tool to evaluate body composition and is often considered as the gold standard in clinical practice. Bioelectrical impedance analysis (BIA) could
F. Buckinx, J. Reginster, N. Dardenne, Jean-Louis Croisiser, J. Kaux, C. Beaudart, J. Slomian, O. Bruyère   +7 more
semanticscholar   +1 more source

How should a DEXA scan be used to evaluate bisphosphonate therapy for osteoporosis? [PDF]

, 2005
If bone density is evaluated after initiating bisphosphonate drug therapy, it should be tested no earlier than 2 years (strength of recommendation [SOR]: B, based on case series of dual energy x-ray absorptiometry [DEXA] scanning precision and ...
Easterling, Lisa, Koval, Peter G., Mackler, Leslie, Pettus, Dawn   +3 more
core  

Can Hounsfield Unit Evaluation of Preoperative CT Scans Predict Surgeon's Preference of Cementless Fixation in Total Knee Arthroplasty?

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Adequate bone quality is necessary for reliable cementless fixation during total knee arthroplasty (TKA). Hounsfield Units (HUs) can be a useful surrogate of bone density, and therefore a proxy of bone quality. We sought to determine whether HU would correlate with subjective intraoperative assessment of bone quality and hence use of ...
Chukwuemeka U. Osondu, Hannah Mosher, Jonathan Brutti, Hallie B. Remer, Matthew Barra, Juan C. Suarez   +5 more
wiley   +1 more source

Genetic markers as instrumental variables: an application to child fat mass and academic achievement [PDF]

The use of genetic markers as instrumental variables (IV) is receiving increasing attention from economists. This paper examines the conditions that need to be met for genetic variants to be used as instruments.
Carol Propper, Debbie A. Lawlor, Frank Windmeijer, George Davey Smith, Stephanie von Hinke Kessler Scholder   +4 more
core   +3 more sources

Childhood obesity and skeletal-dental maturity [PDF]

, 2012
The aim of this cross-sectional study was to evaluate the skeletal maturation assessed through cervical vertebral maturation (CVM) and dental age, in normal weight, pre-obese and obese patients, using the Body Mass Index (BMI) and the Dual energy X-ray ...
Condò, R, Costacurta, M, De Lorenzo, A, Di Renzo, L, Docimo, R, Sicuro, L   +5 more
core  

Body composition in patients with obesity‐related heart failure with preserved ejection fraction: A comparison study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Appendicular lean mass index is a major determinant of cardiorespiratory fitness in patients with obesity‐related heart failure with preserved ejection fraction (HFpEF). Moreover, appendicular lean mass index can be used to diagnose sarcopenia and sarcopenic obesity in this population.
Hannah Salmons, Syed Imran Ahmed, Hayley E. Billingsley, Alexander Reavey‐Cantwell, Roshanak Markley, Michele Golino, Marco Giuseppe Del Buono, Juan Ignacio Damonte, Sebastian Pinel, R. Lee Franco, Antonio Abbate, Carrie P. Earthman, Salvatore Carbone   +12 more
wiley   +1 more source

Validation of rapid 4-component body composition assessment with the use of dual-energy X-ray absorptiometry and bioelectrical impedance analysis

American Journal of Clinical Nutrition, 2018
Background The 4-component (4C) model is a criterion method for human body composition that separates the body into fat, water, mineral, and protein, but requires 4 measurements with significant cost and time requirements that preclude wide clinical use.
B. K. Ng, Y. E. Liu, Wei Wang, T. Kelly, K. Wilson, D. Schoeller, S. Heymsfield, J. Shepherd   +7 more
semanticscholar   +1 more source