Results 131 to 140 of about 347,909 (355)

Nonlinear Dual-Mode Control of Variable-Speed Wind Turbines with Doubly Fed Induction Generators

open access: yes, 2010
This paper presents a feedback/feedforward nonlinear controller for variable-speed wind turbines with doubly fed induction generators. By appropriately adjusting the rotor voltages and the blade pitch angle, the controller simultaneously enables: (a ...
Guo, Yi, Jiang, John N., Tang, Choon Yik
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

A transportable 50 kA dual mode lightning simulator [PDF]

open access: yes
A transportable lightning simulator was designed, built and tested, which is capable of delivering more than 50 kA to an 8 micro-H test object. The simulator was designed to be a versatile device in the lightning laboratory while meeting the requirements
Chen, Y. G., Lloyd, S., Salisbury, K.
core   +1 more source

A Dual-Mode Pressure and Temperature Sensor

open access: yesMicromachines
The emerging field of flexible tactile sensing systems, equipped with multi-physical tactile sensing capabilities, holds vast potential across diverse domains such as medical monitoring, robotics, and human–computer interaction. In response to the prevailing challenges associated with the limited integration and sensitivity of flexible tactile sensors,
Jin Chai   +8 more
openaire   +3 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Biosensing analysis based on Au-Cu bimetallic nanoclusters for colorimetric and fluorescent detection of aflatoxin B1 in cereals and milk

open access: yesFood Science and Human Wellness
Aflatoxin B1 (AFB1) in food is a threaten to food safety and human health. In this study, a colorimetric and fluorescent dual-mode aptamer sensor was constructed for rapid and accurate detection of AFB1 based on polyvinylpyrrolidone-gold-copper ...
Hui Deng   +8 more
doaj   +1 more source

Gas Permeation through Glassy Polymer Membranes with High Glass Transition Temperature [PDF]

open access: yes, 2001
The sorption equilibria and permeation rates for carbon dioxide in such glassy polymer memrbanes with high glass-transition temperature as polyimide, polyetherimide, polysulfone and polyethersulfone membranes, were measured.
Seong-Youl Bae   +2 more
core   +1 more source

Dual Modes of Gene Regulation by CDK12

open access: yes
The process of transcription is driven forward by the activity of kinases including CDK7, CDK9 and CDK12. Accordingly, acute inhibition of any of these kinases results in profound downregulation of gene expression. Here, we discover that loss or inhibition of CDK12 also significantly upregulates a set of coding and non-coding loci, whose activation ...
Yubao Wang   +9 more
openaire   +2 more sources

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