Results 211 to 220 of about 347,909 (355)

An Investigation into the Feasibility of Using a Dual-Combustion Mode Ramjet in a High Mach Number Tactical Missile.

, 1987
Clifford B. Vaught
openalex   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

An integrative deep learning model based on dual-mode ultrasound for diagnosing gallbladder polyps. [PDF]

Insights Imaging
Tang C, Shi Y, Wang L, Zhao X, Li C, Guan P, Geng Z, Chen J, Yu Q, Wang W, Zhu XX, Yuan H.   +11 more
europepmc   +1 more source

The dual mode sorption and diffusion of NaCI at 98℃ in pre-cooked egg white : Rapid communication

, 2004
浩子 橋場, 勢子 根本, ヒロミ 牛腸, 二郎 小見山, ヒロコ ハシバ, セイコ ネモト, ヒロミ ゴチョウ, ジロウ コミヤマ, Hiroko Hashiba, Seiko Nemoto, Hiromi Gocho, Jiro KOMIYAMA   +11 more
openalex   +1 more source

Dual Mechanisms of Ethanol-Impaired Placentation: Experimental Mode

, 2013
Füsun Gündoğan
openalex   +1 more source

Individually Regulated Dual-Output IPT System Based on Current-Mode Switching Cells

, 2020
Xiaoqiang Wang, Jianping Xu, Minrui Leng, Hongbo Ma, Tomislav Dragičević   +4 more
openalex   +2 more sources