Results 191 to 200 of about 347,909 (355)

ANALYSIS OF THE OPERATION MODES OF THE SHIP DUAL CURRENT SYSTEM

, 2019
Oleg Anatolevich Burmakin, Sergey Vasilevich Popov, V.V. Gulyaev, Yuriy Sergeevich Malyshev   +3 more
openalex   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Plasmonic Metal-Phenolic Network Nanoprobes for Multiplex Dual-Mode Immunophenotyping. [PDF]

Nano Lett
González-Cabaleiro L, Lin Z, Vázquez-Iglesias L, Fernandes S, Rodal-Cedeira S, Bodelón G, Pérez-Juste J, Caruso F, Pastoriza-Santos I.   +8 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

A Dual-Mode Flexible Sensor with Capacitive-Resistive Hybrid Response for Bolt Loosening Monitoring. [PDF]

Sensors (Basel)
Ping Y, Li K, Yuan C, Guo D, Yang Y.
europepmc   +1 more source

Intracavity KTP-based OPO pumped by a dual-loss modulated, simultaneously Q-switched and mode-locked Nd:GGG laser

, 2014
Hongwei Chu, Shengzhi Zhao, Kejian Yang, Jia Zhao, Yufei Li, Dechun Li, Guiqiu Li, Tao Li, Wenchao Qiao   +8 more
openalex   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Deep learning-enhanced dual-mode multiplexed optical sensor for point-of-care diagnostics of cardiovascular diseases. [PDF]

Light Sci Appl
Han GR, Eryilmaz M, Goncharov A, Li Y, Ye S, Tomoeda A, Ngo E, Scussat M, Wang X, Ji Z, Zhang M, Hsu JJ, Garner OB, Di Carlo D, Ozcan A.   +14 more
europepmc   +1 more source

Expanding luminol activity: UV-enhanced peroxidase-like activity for dual-mode wide-pH biosensing

Mohamed Hassan Mahana, Syed Rahin Ahmed, Poushali Das, Seshasai Srinivasan, Amin Reza Rajabzadeh   +4 more
openalex   +2 more sources

High-Resolution Velocimetry of a Dual-Mode Scramjet Flameholder

, 2018
Damien Lieber
openalex   +1 more source