Results 181 to 190 of about 294,982 (267)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Dual Mode Vehicle (DMV) Overview

IATSS Research, 2007
doaj   +1 more source

Ball milled magnetic sand as a dual-mode fluorescent sensor: turn-on detection of chlorpyrifos and turn-off response to glyphosate. [PDF]

Nanoscale Adv
Qureashi A, Bashir A, Nazir I, Haq ZU, Ganaie FA, Pandith AH, Sheikh FA.   +6 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Stack of Bi₂Se₃/Carbon Films with Pyramid Interface for Dual-Mode Temperature-Pressure Sensing in Aquatic Environments. [PDF]

Nanomicro Lett
Xu Y, Zhang X, Lou S, Tang Z, Xie D, Zhang C, Chen M, Liu H, Sun C, Ou Y, Zong PA.   +10 more
europepmc   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Dual-Band Bent Sensing Textile Antenna Under Dual-Mode Resonance. [PDF]

Sensors (Basel)
Liu ZQ, Chen N, Ma K, Luo YC, Mao XH, Qi JC, Li XH, Lu WJ.   +7 more
europepmc   +1 more source

Profound Leadership Strategies: Transcending the Leadership Crisis in the Age of Artificial Intelligence

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article examines the evolving role of organizational leadership amidst the rapid advancements in artificial intelligence (AI). It explores a broadly experienced and documented crisis in leadership, due in part to the disruptive nature of AI and emerging technology.
Rachel Wlodarsky, Davin Carr Chellman
wiley   +1 more source

AI-Assisted Self-Powered Wearable Dual-Mode Sensor With TENG and Stretchable Optical Fiber for Neurological Disorder Diagnostics. [PDF]

Adv Sci (Weinh)
Li T, Liu H, Liu G, Wang Q, Zhou H, Liu G, Xu Y, Wang J, Wang Z, Zhu F, Luo F, Wang ZL, Zhang C.   +12 more
europepmc   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source