Results 101 to 110 of about 14,062,695 (299)
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Detecting response styles by using dual scaling of successive categories [PDF]
A response style denotes a certain mapping of latent preferences toa rating scale that is common among a certain group of individuals.For example, individuals from the same country may assign highratings to the majority of objects regardless of the ...
Velden, M. van de
core +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
The present location of temporal embeddedness: the case of time linked consumption practices in dual career families [PDF]
, 2009 This paper examines the time linked consumption practices of professional dual career families, examining the kind of consumption practices these families use to manage their lives.
Bettany, S., Gatrell, C.
core
Education SciencesThe aim of this study was to compare the socio-demographic, sporting characteristics and perceptions of student-athletes with disabilities of perceived barriers according to the state system of dual career support. Two hundred and twelve student-athletes
Alejandro Leiva-Arcas +13 more
doaj +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
BMC SurgeryBackground This study employed a retrospective analysis to compare the short-term efficacy of the medial and lateral dual incision approach versus the medial dual incision approach for endoscopic spur resection combined with plantar fascia release in the
Xuehai Dong +4 more
doaj +1 more source
Miniature Multi-Target Tracking in Sonar Images Using Dual Trajectory Storage Method
Journal of Marine Science and EngineeringTo address the conflict between trajectory fragmentation and the trade-off between association efficiency and data integrity in underwater micro-scale multi-target sonar motion detection and tracking in video sequences, a multi-target motion detection ...
Zhen Huang +6 more
doaj +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source