Results 41 to 50 of about 14,062,695 (299)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Nowadays, both BDS-3 and Galileo can provide global positioning and navigation services. This contribution carried out a comprehensive analysis and validation of positioning performance in terms of positioning accuracy (RMS) and convergence time, which ...
Zunyao Hou, Feng Zhou
doaj +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Consists of film clips of World War II events, including Mussolini\u27s invasion of Ethiopia and Hitler\u27s march into Austria.
Time-Life Video
core
Adaptive Partitioning for Large-Scale Dynamic Graphs [PDF]
—In the last years, large-scale graph processing has gained increasing attention, with most recent systems placing particular emphasis on latency. One possible technique to improve runtime performance in a distributed graph processing system is to reduce
Martella, Claudio +13 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Small scale power generation using a dual fuel system [PDF]
Single-cylinder diesel engines are widely utilized in Malaysia to generate electricity on smallscales in open markets and rural areas. This paper presents a brief study carried out to:(i) understand the nature of exhaust emissions (NOx , CO and CO2 ...
Al-Atabi, Mushtak Talib Ali +2 more
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Velocimetry of red blood cells in microvessels by the dual-slit method: Effect of velocity gradients [PDF]
The dual-slit is a photometric technique used for the measurement of red blood cell (RBC) velocity in microvessels. Two photometric windows (slits) are positioned along the vessel.
Duru, Paul +3 more
core +1 more source
To fully exploit the potential regulation capacity of high-energy-consuming industrial loads and alleviate the pressure on the supply-demand balance of power systems caused by the large-scale access of renewable energy resources, this paper proposes a ...
WANG Jiaying, LU Chunguang, JIAO Wenshu, WU Qiuwei, CAO Yongji, YANG Jianli
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source

