Results 41 to 50 of about 535,352 (239)

Queue-Aware Cell Activation and User Association for Traffic Offloading via Dual-Connectivity

IEEE Access, 2019
With the objective of reducing energy cost, we study the stochastic optimization of traffic off-loading via dual-connectivity by joint cell activation and user association.
Qiaoni Han, Bo Yang, Xiaocheng Wang
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

State of Health Prediction of Lithium-Ion Batteries Based on Dual-Time-Scale Self-Supervised Learning

Batteries
Accurate estimation of the state of health (SOH) of lithium-ion batteries confronts two critical challenges: the extreme scarcity of labeled data in large-scale operational datasets and the mismatch between existing methods (relying on full charging ...
Yuqi Li, Longyun Kang, Xuemei Wang, Di Xie, Shoumo Wang   +4 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Intent-driven dual-time-scale resource allocation approach for Internet of things

物联网学报
With the development of IoT technologies, the demand for quality of service across different business scenarios has become increasingly diverse. Currently, how to accurately interpret IoT service requirements and effectively guarantee quality of service (
Song Hang, Cai Jian, Yuan Yundong, Zhang Yu, Liu Rui, Wang Jiansu, Liu Gang, Zhang Min, Wang Jingyu   +8 more
doaj   +2 more sources

Dynamic Behavior Analysis of Complex-Configuration Organic Rankine Cycle Systems Using a Multi-Time-Scale Dynamic Modeling Framework

Entropy
Organic Rankine Cycle (ORC) systems with complex configurations exhibit strong thermo-mechanical–electrical–magnetic coupling, making dynamic analysis computationally demanding.
Jinao Shen, Youyi Li
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Centralized Shared Energy Storage Optimization Framework for AC/DC Distribution Systems with Dual-Time-Scale Coordination

Applied Sciences
Conventional shared energy storage (SES) allocation and coordinated operation mechanism are mismatched with the actual time-varying demand of the distribution system, resulting in low utilization of energy storage and renewable energy sources (RES ...
Yidi Zhu, Qian Xiao, Hongjie Jia, Wenbiao Lu, Yu Jin   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source