Results 151 to 160 of about 3,000,597 (358)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Duality in Mechanics [PDF]

open access: bronze, 1952
P. Le Corbeiller, Ying-Wa Yeung
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Progressive outer retinal necrosis: Dual virus involvement

open access: yesIndian Journal of Ophthalmology, 2020
Bruttendu Moharana   +4 more
doaj   +1 more source

Una estimación de la productividad total de factores en el Perú: un enfoque primal y dual

open access: yesEconomía, 2014
En este trabajo hemos estimado el crecimiento de la productividad total de los factores (PTF) para la economía peruana usando los métodos primal y dual para el período de 2003-2012.
Nikita Céspedes   +1 more
doaj  

Home - About - Disclaimer - Privacy