Results 81 to 90 of about 1,596,902 (278)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

How Career and Non-Work Goal Progress Affect Dual Earners’ Satisfaction: A Whole-Life Perspective [PDF]

Many career self-management models assume that career goal progress promotes satisfaction, but research on the topic has yielded mixed results. Adopting a whole-life perspective, this study examines how career and non-work goal progress relate to career,
Verbruggen, Marijke, Abraham, Elisabeth, Hirschi, Andreas   +2 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Dual careers as sustainable careers for performing artists in times of crisis. A contextual approach to the construct of a sustainable arts career.

PLoS ONE
For an individual, a sustainable career is a sequence of events in one's professional life that both brings professional satisfaction to the career actor, but also allows them to stay healthy, fit, satisfied with their non-work life, feel stable and ...
Patrycja Mizera-Pęczek, Anna Krasnova, Magdalena Sasin, Aleksandra Sieczych-Kukawska   +3 more
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

A review of the institutional landscape for dual-career hiring in higher education

Discover Education
Meeting the needs of dual-career academic couples has become an important part of university efforts to foster family-friendly workplaces. Many universities have developed formal or informal approaches to addressing dual-career issues, but variation ...
Torin Monahan, Margaret Waltz, Amelia Parker, Jill A. Fisher   +3 more
doaj   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

career service papers - csp 17/19

, 2019
Themen dieser Ausgabe sind veränderte Anforderungen an Hochschule und Arbeitgeber*innen (Generation Z), Beiträge zu studentischen Praktika und zur Qualitätssicherung von Praktika, ein Beitrag zur Beschäftigungsfähigkeit und Qualitätssicherung im Rahmen ...
Dorenburg, Christiane, Buchwald, Christine, Schröder, Andrea, Assel, Jessica, Menke, Marcellus, Aufurth, Ludmilla, Balks, Anne-Dörte, Strübel, Lisa, Vedder, Günther, Waldermann, Clara Maria   +9 more
core   +1 more source

Dual-earner and dual-career couples in contemporary Italy

Journal of Family Research, 2007
Based on a national longitudinal data set, this essays analyses the conditions that favour the formation of dual earner, and specifically dual-career couples in Italy, i.e., in a country characterized by comparatively low women’s labour force participation and intra-generational mobility.
Schizzerotto, Antonio, Saraceno, Chiara, M. Lucchini   +2 more
openaire   +7 more sources