Results 61 to 70 of about 1,596,902 (278)
Career service papers - csp 19/22
, 2022 Themen dieser Ausgabe sind der Unterschied zwischen klassischen und online geführten Vorstellungsgesprächen, die Vorstellung eines Evaluationsverfahrens für Beratungen, der Beitrag von Praxisphasen zum Studienerfolg, die Unterschiede von Praktika im ...
Magnamino, Carla +9 more
core +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
BBR: Brazilian Business Review, 2017 Couples who live a dual career, in general, are characterized by their continuing professional engagement and their desire for personal growth together. It is a synergy between career aspirations and family sphere, so that they co-exist;
Heliani Berlato, Karen Florencio Corrêa
doaj
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
مجله علوم روانشناختی, 2021 Background: In the families of dual career couples, where both spouses have an income, the quantity and severity of marital conflicts are different from those of single-employed families.
rohollah rahimi, Sodabeh Ershadimanesh
doaj
Media Statistika, 2012 Currently, the role of women has shifted from traditional to modern roles. From only a traditional role to bear children and run the household, women now have a social role which can be a career with supported higher education.
Nova Nova, Dwi Ispriyanti
doaj +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Work, Inequality, and the Dual Career Household [PDF]
Dual career households have the potential to be the most egalitarian of all households. However, while paid work is increasingly distributed evenly between career men and women, household time remains a social constraint for many women.
Dan Wheatley and Zhongmin Wu
core
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source