Results 41 to 50 of about 1,596,902 (278)

Spirituality, dual career family worker, demographic factors, and organizational commitment: evidence from religious affairs in Indonesia

Indonesian Journal of Islam and Muslim Societies, 2017
The purpose of this study is to specify whether spirituality, age, and tenure have an effect on organizational commitment and to determine whether the moderating variables, i.e.
Abdul Aziz Nugraha Pratama, Hikmah Endraswati   +1 more
doaj   +1 more source

Análisis de la carrera dual en deportistas peruanos de alto rendimiento

Revista de Psicología Aplicada al Deporte y al Ejercicio Físico, 2021
El objetivo del presente estudio es hacer un análisis descriptivo de la carrera dual (compaginar estudios y deporte) en deportistas peruanos que compiten a nivel internacional. Mediante una encuesta que recogía información sobre datos personales, entorno
Jorge Moreno-Peña, Saúl Chacaliaza Briones, Alex Robles Gutierrez   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

'WOMEN OF CAREER': WORK AS A VALUE AND A SOURCE OF EMPOWERMENT

Colloquium, 2020
The author analyses categories of work and career, understood as the space of experiencing personal satisfaction and self-efficacy. In this regard work has an emancipatory function, especially for women, for whom professional activity is a way to become ...
Joanna Ostrouch-Kamińska
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Facilitating sport and study: The case of a dual career development environment in Sweden

, 2020
This case study of a dual career development environment (DCDE) was informed by the holistic ecological approach (HEA) and aimed at: (a) providing a holistic description of a DCDE at university level in Sweden, and (b) investigating the factors ...
Linnér, Lukas, Küttel, Andreas; id_orcid, Kuettel, Andreas,, Stambulova, Natalia,, Henriksen, Kristoffer,, Storm, Louise Kamuk; id_orcid, Henriksen, Kristoffer; id_orcid, Linnér, Lukas,, Stambulova, Natalia, Kamuk Storm, Louise,   +9 more
core   +1 more source

Dual sport career experiences of student-athletes studying in South Africa and the USA

African Journal of Career Development
Background: Institutions of higher education are hubs for student-athletes pursuing dual careers, in sports and higher education. The concepts of dual careers, transition models and support systems for student sports provide the conceptual framework for ...
Louis J. van Zyl
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source