Results 71 to 80 of about 403,869 (278)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Compare and contrast between duals of fusion and discrete frames

open access: yes, 2016
Fusion frames are valuable generalizations of discrete frames. Most concepts of fusion frames are shared by discrete frames. However, the dual setting is so complicated.
Arefijamaal, Ali Akbar, Osgooei, Elnaz
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Continuous Frames Under the Weighted Composition Operators on the Weighted Bergman Space

open access: yesAxioms
We investigate the behavior of continuous frames in the weighted Bergman space Aα2 over the unit disc under the action of weighted composition operators. Motivated by developments in the discrete frame setting, we provide a comprehensive characterization
Fatma Bozkurt, Faruk Yilmaz
doaj   +1 more source

Operator Characterizations and Some Properties of g-Frames on Hilbert Spaces

open access: yesJournal of Function Spaces and Applications, 2013
Given the g-orthonormal basis for Hilbert space H, we characterize the g-frames, normalized tight g-frames, and g-Riesz bases in terms of the g-preframe operators.
Xunxiang Guo
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

On generation and properties of triple sequence-induced frames in Hilbert spaces

open access: yesJournal of Numerical Analysis and Approximation Theory
In this paper, we present the innovative idea of ”t-frames,” frames produced by triple sequences within Hilbert spaces. The paper explores various properties of these t-frames, delving into topics like frame operators, alternative dual frames, and the ...
Asif H. Jan   +3 more
doaj   +1 more source

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