Results 151 to 160 of about 211,702 (296)

Gap Analysis of Ship Design Approval Case Study: Key Plan Drawing Assessment for Dual Fuel Harbour Tugboat

International Journal of Offshore and Coastal Engineeing, 2023
Iskendar Iskendar, Abdul Kadir, Waluyo Waluyo, Dewi Kartikasari, Siti Sadiah, Dany Hendrik Priatno, Andi Cahyo Prasetyo Tri Nugroho, Fredhi Agung Prasetyo   +7 more
openaire   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Gender Wage Differentials in a Competitive Labor Market: The Household Interaction Effect

We present a theoretical explanation of the gender wage gap which turns on the interaction between men and women in households.In equilibria where men are over-represented in full-time work, we show that firms rationally choose to hire women only at ...
Francois, P., Ours, J.C. van
core  

Singletrack: an algorithm for improving memory consumption and performance of gap-affine sequence alignment. [PDF]

Bioinformatics
López-Villellas L, Iñiguez C, Jiménez-Blanco A, Aguado-Puig Q, Moretó M, Alastruey-Benedé J, Ibáñez P, Marco-Sola S.   +7 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Dual Band-Pass Filter Based on Split Ring Resonators with Controlled Asymmetric Bandwidth Response. [PDF]

Sensors (Basel)
Castillo-Araníbar P, Lampérez AG, Segovia-Vargas D.   +2 more
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Synergistic anion-cation descriptor for bidirectional electrocatalyst in Li-CO₂ battery. [PDF]

Sci Adv
Zhai X, Liu Y, Luo M, Wei T, Wang H, Zhang J, Su L, Fan Z, Sun Z, Zhang Z, Wu L, Zhang H, Ye B, Zhou M.   +13 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

FS/DS : A Theoretical Framework for the Dual Analysis of Feature Space and Data Space

With the surge of data-driven analysis techniques, there is a rising demand for enhancing the exploration of large high-dimensional data by enabling interactions for the joint analysis of features (i.e., dimensions).
El-Assady, Mennatallah, Miller, Matthias, Dennig, Frederik L., Keim, Daniel A.   +3 more
core   +1 more source