Results 61 to 70 of about 111,971 (236)

Memory, learning and language in autism spectrum disorder [PDF]

open access: yes, 2018
Background and aims: The ‘dual-systems’ model of language acquisition has been used by Ullman and colleagues to explain patterns of strength and weakness in the language of higher-functioning people with autism spectrum disorder (ASD).
Bodison S.   +9 more
core   +2 more sources

Organ‐Specific and Conserved Regulatory Logic Orchestrates Gene Expression in the Embryonic Mesothelium

open access: yesAdvanced Science, EarlyView.
Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang   +3 more
wiley   +1 more source

Nigra‐Subthalamic Dopaminergic Circuitry Modulates and Represents Distinct Pain Modality in Physiological and Pain States in Mice

open access: yesAdvanced Science, EarlyView.
Nigral dopaminergic (DA) neurons modulate and represent pain with a preference to a particular modality (mechanical) and laterality (contralateral), which are controlled by nigral GABAergic neurons. The pain modulation is mimicked by the nigro‐subthalamic projection and its downstream neurons, involving D2‐like receptors.
Ying Ji   +13 more
wiley   +1 more source

Institutional Cognition [PDF]

open access: yes, 2006
We generalize a recent mathematical analysis of Bernard Baars' model of human consciousness to explore analogous, but far more complicated, phenomena of institutional cognition. Individual consciousness is limited to a single, tunable, giant component of
Wallace, Deborah, Wallace, Rodrick
core  

Corals and Reef‐Dwelling Fish Regulate Carbon Storage and Cycling Processes in Coral Reef Ecosystems

open access: yesAdvanced Science, EarlyView.
Coral reefs are biodiversity hotspots, yet their role in carbon storage and cycling remains poorly understood. Using field surveys and modeling in the South China Sea, we reveal the overlooked potential of carbon storage in reef ecosystems and how reef fish, corals, and surface sediment jointly shape reef carbon reservoirs.
Yiting Chen   +8 more
wiley   +1 more source

The acquisition of tense-aspect morphology and the regular-irregular debate [PDF]

open access: yes, 2013
This paper reviews research on English past-tense acquisition to test the validity of the single mechanism model and the dual mechanism model, focusing on regular-irregular dissociation and semantic bias.
Shirai, Yasuhiro
core  

A Guide for Spatial Omics Technologies: Innovation, Evaluation, and Application

open access: yesAdvanced Science, EarlyView.
This review presents a strategy‐centric framework for spatial omics technologies, organizing methods by how spatial information is experimentally encoded. It compares key performance trade‐offs across sequencing‐ and imaging‐based approaches, examines computational and practical limitations, and highlights biomedical applications. The analysis provides
Xiaofeng Wu   +5 more
wiley   +1 more source

Biologically inspired distributed machine cognition: a new formal approach to hyperparallel computation [PDF]

open access: yes, 2007
The irresistable march toward multiple-core chip technology presents currently intractable pdrogramming challenges. High level mental processes in many animals, and their analogs for social structures, appear similarly massively parallel, and recent ...
Wallace, Rodrick
core  

Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion

open access: yesAdvanced Science, EarlyView.
The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li   +10 more
wiley   +1 more source

Morphosyntactic Aspects of Ocaina: Between Genetic Features (Witotoan family) and Areal Influences

open access: yesMundo Amazónico, 2010
This paper presents some morphosyntactic features of Ocaina, a seriously endangered, underdescribed language of the Colombian-Peruvian Amazon region. Ocaina has an extensive nominal classification system and number markers—dual  and plural—suffixed to ...
Doris Fagua Rincón, Frank Seifart
doaj  

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