Results 121 to 130 of about 1,157,757 (252)
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Role of immunotherapy in gastrointestinal malignancies
This thesis explores the role of immunotherapy in gastrointestinal malignancies, including colorectal, liver, esophageal, pancreatic, and gastric cancers. It outlines key immunotherapeutic strategies such as immune checkpoint inhibitors, cancer vaccines,
Ho Hoang Bao, Chau
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Dental consequences of malignant hematological patient infections
, 2018 How patients with hematological malignancies are more susceptible to developing infection such as bacterial, viral and fungal during treatment and their dental consequences and management.
Khokhar, Haseeb
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Clinical and Translational AllergyImmune dysregulation has been widely recognized in the international literature as an underlying condition for hematological malignancies and allergic disorders.
Stefania Isola +5 more
doaj +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
, 2022 Mapping of Dual-Use related ITTs in EUP2P partner countries and other third countries through “TIM Dual ...
Guest, Clara +2 more
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Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro +6 more
wiley +1 more source
Discover OncologySpindle cell malignancies of the oral cavity are uncommon and pose considerable diagnostic challenges due to overlapping histomorphology and immunohistochemical features.
Sreedevi Jakka +2 more
doaj +1 more source
Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu +7 more
wiley +1 more source
Recent Progress of Exosomes in Hematological Malignancies: Pathogenesis, Diagnosis, and Therapeutic Strategies [PDF]
Hu Zhang,1,* Jingyi Xia,2,* Xueqing Wang,1 Yifan Wang,2 Jie Chen,3 Lin He,1 Jingying Dai2 1Department of Pharmacy, Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science ...
Xia J +6 more
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