Results 181 to 190 of about 3,030,814 (325)

Thyroid hormone plus dual-specificity phosphatase-5 siRNA increases the number of cardiac muscle cells and improves left ventricular contractile function in chronic doxorubicin-injured hearts

, 2021
Lin Tan, Nikolay Bogush, Emmen Naqvi, John W. Calvert, Robert M. Graham, W. Robert Taylor, Nawazish Naqvi, Ahsan Husain   +7 more
openalex   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

New gait performance indices and cognitive functions: a pilot study on correlation in people with Parkinson's disease. [PDF]

Front Hum Neurosci
Cocco ES, Thouant CL, Pietrosanti L, Infarinato F, Manzia CM, Romano P, Torcisi RSM, Franceschini M, Verrelli CM, Pournajaf S.   +9 more
europepmc   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

scRNA+TCR-seq reveals the proportion and characteristics of dual TCR Treg cells in mouse lymphoid and non-lymphoid tissues. [PDF]

Elife
Xu Y, Peng Q, Lu X, Ma L, Li J, Yao X.
europepmc   +1 more source

Dual Numbers for Algorithmic Differentiation

, 2019
"The cubic spline interpolation method, the Runge–Kutta method, and the Newton–Raphson method are extended to dual versions (developed in the context of dual numbers). This extension allows the calculation of the derivatives of complicated compositions of functions which are not necessarily defined by a closed form expression.
F. Peñuñuri, O. Carvente, M.A. Zambrano-Arjona, R. Peón, Carlos A. Cruz-Villar   +4 more
openaire   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Long-Term Outcomes of Anticoagulation Monotherapy Versus Combination Therapy in Atrial Fibrillation Patients with Complex Coronary Artery Disease. [PDF]

Med Sci Monit
Lee WC, Chang WT, Hong CS, Lin CH, Chiang CY, Huang PC, Chen ZC, Shih JY, Fang HY.   +8 more
europepmc   +1 more source

The Impact of the Number of Dual Enrollment Credits on Racial Minority Students’ Completion Time at Five Virginia Community Colleges

, 2018
Elizabeth Gardiner Dingess
openalex   +2 more sources

A new property of the Lovász number and duality relations between graph parameters [PDF]

, 2016
Antonio Acín, Runyao Duan, David E. Roberson, Ana Belén Sainz, Andreas Winter   +4 more
openalex   +1 more source