Results 251 to 260 of about 906,823 (306)

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Fine-scale predictive modeling of Aedes mosquito abundance and dengue risk indicators using machine learning algorithms with microclimatic variables. [PDF]

Sci Rep
Dom NC, Abdullah NAMH, Dapari R, Salleh SA.   +3 more
europepmc   +1 more source

A Novel Approach for Estimating the Effective Atomic Number Using Dual Energy

JeongHeon Kim, So Hyun Ahn, Kwangwoo Park, Jin Sung Kim   +3 more
openalex   +1 more source

Genetic Modifiers of Parkinson's Disease: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the associations of LRRK2 p.G2019S, GBA1 p.N409S, polygenic risk scores (PRS), and APOE E4 on PD penetrance, risk, and symptoms. Methods We conducted a US‐based observational case–control study using data from the 23andMe Inc. and Fox Insight Genetic Substudy (FIGS) databases.
Matthew J. Kmiecik, Michael V. Holmes, Pierre Fontanillas, Giulietta M. Riboldi, Ruth B. Schneider, Jingchunzi Shi, Anna Guan, Susana Tat, Steven Micheletti, Keaton Stagaman, Josh Gottesman, David A. Hinds, Joyce Y. Tung, 23andMe Research Team, Stella Aslibekyan, Lucy Norcliffe‐Kaufmann   +15 more
wiley   +1 more source

Network design for bypass roads using interval valued fuzzy outerplanar graphs. [PDF]

Sci Rep
Jaisankar D, Ramalingam S, Deivanayagampillai N, Walelign T.   +3 more
europepmc   +1 more source

Longitudinal Study of Salivary Biomarkers in the Definition of Clinico‐Molecular Progression of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
Longitudinal changes in salivary biomarkers in Parkinson’s disease (PD) from early (T0) to 4‐year follow‐up (T1), quantified by ELISA: oligomeric and total α‐synuclein, total and phosphorylated tau, MAP1LC3B (autophagy), and TNFa (inflammation). Blue arrows indicate direction of change at T1 vs T0 (up = increase; down = decrease).
Maria Ilenia De Bartolo, Daniele Belvisi, Matteo Costanzo, Claudia Caturano, Francesco Emanuele Bellomi, Carolina Cutrona, Flavia Aiello, Giorgio Leodori, Massimo Marano, Romina Mancinelli, Antonella Conte, Giovanni Fabbrini, Alfredo Berardelli, Giorgio Vivacqua   +13 more
wiley   +1 more source

Effectiveness and safety of early add-on therapy with brivaracetam in patients with poorly controlled focal seizures in routine clinical practice: BRIV-add study. [PDF]

Epilepsia Open
Serrano-Castro PJ, Caballero-Martínez F, Campos-Lucas FJ, Campos-Fernández D, de Aguilar-Amat MJ, García A, Gifreu A, Santamaría-Rodríguez I, Poza JJ, Toledo-Argany M, Grupo de Investigadores Colaboradores.   +10 more
europepmc   +1 more source

Dual Scalable Annealing Processing System that Scales Number of Spins and Interaction Bit Width Simultaneously

Dong Cui, Taichi Megumi, Akari Endo, T. Kawahara   +3 more
openalex   +1 more source

Commentary on "Complex left main bifurcation PCI in a patient with dual positivity: A unique interventional approach - A case report" by Setty et al., 2025. [PDF]

Int J Surg Case Rep
Momeni MK, Khozeimeh E, Moulaei N, Zivarifar H.   +3 more
europepmc   +1 more source

Rapid Quantification of IS6110 Copy Number in M. tuberculosis Using Dual-Target qPCR Assay

Dinshaw J. Patel, Krishna Himmatbhai Goyani, Shalin Vaniawala, Pratap N. Mukhopadhyaya   +3 more
openalex   +1 more source