Results 131 to 140 of about 1,451,548 (325)
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
Effects of Counting the Stride Numbers as A Secondary Task on Gait in People with Parkinson’s Disease: An Idea About the Cause of Dual Task Interference During Gait and A New Hope for Early Diagnosis [PDF]
, 2018 Yashar Sarbaz, Hakimeh Pourakbari
openalex +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
A simple and robust method for simultaneous dual-omics profiling with limited numbers of cells
, 2021 Ruifang Li, Sara A. Grimm, Paul A. Wade
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Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
Dual Numbers for Algorithmic Differentiation
, 2019 "The cubic spline interpolation method, the Runge–Kutta method, and the Newton–Raphson method are extended to dual versions (developed in the context of dual numbers). This extension allows the calculation of the derivatives of complicated compositions of functions which are not necessarily defined by a closed form expression.
F. Peñuñuri +4 more
openaire +1 more source
Molecular Oncology, EarlyView.Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva +5 more
wiley +1 more source
Characterizations and properties of hyper-dual Moore-Penrose generalized inverse
AIMS MathematicsIn this paper, the definition of the hyper-dual Moore-Penrose generalized inverse of a hyper-dual matrix is introduced. Characterizations for the existence of the hyper-dual Moore-Penrose generalized inverse are given, and a formula for the hyper-dual ...
Qi Xiao, Jin Zhong
doaj +1 more source
A self-dual poset on objects counted by the Catalan numbers and a type-B analogue
, 2000 Miklós Bóna, Rodica Simion
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