Results 41 to 50 of about 265,109 (310)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan +3 more
wiley +1 more source
Study of Pipeline Steels with Acicular Ferrite Microstructure and Ferrite-bainite Dual-phase Microstructure [PDF]
Materials Research, 2015 Three kinds of X70 steels with the same chemical composition and different microstructures fabricated by varying processes were compared in aspect of the microstructures and mechanical properties using SEM, TEM and tensile testing machine.
Xiurong Zuo, Zhengyue Zhou
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
On the law of mixtures in dual-phase steels [PDF]
Metallurgical Transactions A, 1980 The applicability of the equation of the stress in the ferrite at the ultimate tensile strain to dual-phase steels obtained by heating 1010 and 1020 grades was tested. The law of mixtures describe the tensile strength of 1010 steels provided the dislocation hardening is included.
J. Y. Koo, M. J. Young, G. Thomas
openaire +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Effect of laser welding on microstructure and mechanical behaviour of dual phase 600 steel sheets
Heliyon, 2021 Dual Phase steels are one of the most used advanced high-strength materials in the industry, due to its combination of a ductile ferritic matrix and disperse hard martensite islands, which provide outstanding mechanical properties for components to be ...
Vinicius Machado Mansur +4 more
semanticscholar +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Damage in dual phase steels [PDF]
, 2019 In this research, the effect of microstructural features on damage behavior isstudied with a special emphasis on evolution of plastic deformation heterogeneity in microscale. This is carried out by performing experimental and numerical work on a ferritic-martensitic DP600 steel sheet from the AHSS family.The experimental investigations are focused on ...
openaire +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source