Results 61 to 70 of about 237,627 (302)

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang   +6 more
wiley   +1 more source

Effect of Quenching in Dual-phase Region on Microstructure and Mechanical Properties of 7Ni Steel

open access: yesCailiao gongcheng, 2018
The influence of quenching temperature and holding time in dual-phase region on microstructure and mechanical properties of 7Ni steel was studied by X-ray diffractometer, scanning electron microscopy and thermal dilatometer.
XU Li-xiong, WU Hui-bin, MOU Dan
doaj   +1 more source

Comparison of gurson and lemaitre model in the context of blanking simulation of a high strength steel [PDF]

open access: yes, 2017
The process of blanking takes place in a short band with high accumulated strain undergoing various stress triaxialities. Enhanced implementations for shear and compressive loads of Gurson’s and Lemaitre’s model are directly compared for the same ...
Clausmeyer, Till   +3 more
core  

High-Torque-Density Low-Cost Magnetic Gear Utilizing Hybrid Magnets and Advanced Materials [PDF]

open access: yes, 2019
Two major challenges of existing high-performance magnetic gears are: (i) High content of rare-earth permanent magnets which results in high cost as well as price fluctuation; (ii) Conflict between mechanical and electromagnetic performances, especially ...
Al-Qarni, Ali Hussain   +2 more
core   +2 more sources

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen   +7 more
wiley   +1 more source

Crashworthiness assessment considering the dynamic damage and failure of a dual phase automotive steel

open access: yes, 2020
Analyzing crash worthiness of the automotive parts has been posing a great challenge in the sheet metal and automotive industry since several decades.
Chandran, Sarath, Verleysen, Patricia
core  

Validating performance of automotive materials at high strain rate for improved crash design [PDF]

open access: yes, 2006
This paper investigates sources of performance variability in high velocity testing of automotive crash structures. Sources of variability, or so called noise factors, present in a testing environment, arise from uncertainty in structural properties ...
Bardenheier, R.   +6 more
core  

Microstructural topology effects on the onset of ductile failure in multi-phase materials - a systematic computational approach

open access: yes, 2015
Multi-phase materials are key for modern engineering applications. They are generally characterized by a high strength and ductility. Many of these materials fail by ductile fracture of the, generally softer, matrix phase.
de Geus, T. W. J.   +2 more
core   +2 more sources

Influence of the drece process of severe plastic deformation on the mechanical properties of the ultra-low carbon interstitial free steel [PDF]

open access: yes, 2018
This research paper shows the influence of a repeated SPD (Severe Plastic Deformation) plastic forming with the DRECE technique (Dual Rolls Equal Channel Extrusion) on hardening of low carbon IF steel. The influence of number of passes through the device
Bednarczyk, Iwona   +3 more
core   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

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