Results 41 to 50 of about 4,351 (305)

On the use of thermomechanical processing to enhance the strength-ductility-toughness balance of plain low-carbon steel

open access: yesHeliyon
This study aimed to fabricate a dual-phase (DP) steel with a combination of high strength-ductility-toughness by thermomechanical processing for industrial applications.
Fatemeh Khorasani   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Microstructure and properties of dual-phase steels containing fine precipitates [PDF]

open access: yes, 1981
Very fine particles (carbides or carbonitrides) of the order of 20 A were extensively examined in the ferrite regions of dual-phase steels subjected to intercritical annealing followed by fast quenching to room temperature.
Thomas, G.   +3 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Effect of austempering conditions on the microstructure and mechanical properties of AISI 4340 and AISI 4140 steels

open access: yesJournal of Materials Research and Technology, 2019
AISI 4340 and AISI 4140 are normally used for different structural applications in quenched and tempered state due to their high strength, high abrasion and fatigue resistance but they lack toughness. Presence of dual phase microstructure such as ferrite-
Mian Muhammad Bilal   +6 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Solid state phase transformations in Advanced Steels [PDF]

open access: yes, 2013
In order to achieve progress in Advanced Steels development came more emphasis in solid state phase transformations are received. For achieving the desired mechanical and corrosion resistance properties in Duplex Stainless Steels (DSS), a precise ...
Miranda Pérez, Argelia Fabiola
core  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Enhancement Wear Resistance of Carbon Dual Phase Steel by Cryogenic Treatment

open access: yesمجلة النهرين للعلوم الهندسية, 2014
Dual phase steels containing three different amounts of martensite 21, 37 and 87 Vol. Pct. have been made from carbon steels containing 0.12, 0.33 and 0.43 wt. pct. Carbon respectively.
Abbas A. Hussein, Hussein B. Muhammad
doaj  

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

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