Results 41 to 50 of about 94,464 (307)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Design of a Polarization-Diverse Planar Leaky-Wave Antenna for Broadside Radiation

IEEE Access, 2019
The design of a K-band radial leaky-wave antenna is presented for polarization diversity applications. The antenna structure is constituted by an annular, radially periodic, and metallic strip grating printed on top of a single-layer grounded dielectric ...
Davide Comite, Symon K. Podilchak, Paolo Baccarelli, Paolo Burghignoli, Alessandro Galli, Alois P. Freundorfer, Yahia M. M. Antar   +6 more
doaj   +1 more source

Dual-Band Dual-Linear Polarization Reflectarray for mmWaves/5G Applications

IEEE Access, 2020
A dual-band dual-linear polarization reflectarray configuration is developed for future 5G cellular applications. A single layer unit cell including two pairs of miniaturized fractal patches is designed to operate at two distinct frequencies within the ...
Sandra Costanzo, Francesca Venneri, Antonio Borgia, Giuseppe Di Massa   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Design and simulated characterization of the dual-band polarizer based on metasurface structure

AIP Advances
Dual-band polarizers must simultaneously exhibit high transmittance and bandwidth efficiency in fields such as polarization navigation and efficient detection. However, in most studies, the detection of dual bands is inefficient.
Hangwei Zhu, Yanlin He, Shuning Wang, Lidan Lu, Lianqing Zhu   +4 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Rank-Dependent Measures of Bi-Polarization and Marginal Tax Reforms [PDF]

In this paper, we investigate a dual class of bi-polarization indices, namely rank-dependent bi-polarization indices. We show that these indices may be characterized with the generalized positional transfer sensitivity property.
Paul Makdissi, Stéphane Mussard
core   +2 more sources

Wideband Dual-Polarized PRGW Antenna Array with High Isolation for Millimeter-Wave IoT Applications

Sensors
This work presents a novel dual-polarized antenna array tailored for Internet of Things (IoT) applications, specifically designed to operate in the millimeter-wave (mm-wave) spectrum within the frequency range of 30–60 GHz.
Zahra Mousavirazi, Mohamed Mamdouh M. Ali, Abdel R. Sebak, Tayeb A. Denidni   +3 more
doaj   +1 more source

Exceptional Extended Dual Polar Spaces

European Journal of Combinatorics, 1997
It is considered an extended dual polar space (EDPS). An EDPS \({\mathcal G}\) is called affine if there is a flag-transitive automorphism group \(G\) and a normal subgroup \(T\) in \(G\) such that \(T\) acts regularly on the set of elements of type 1 in \({\mathcal G}\). Theorem. Let \({\mathcal G}\) be an EDPS whose rank is greater than or equal to 3
openaire   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source