Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Application of Dual-Targeting Carbon Dot Nanozymes in Improving Hypoxia and Enhancing Small Interfering RNA-Mediated Gene Silencing for Hepatocellular Carcinoma. [PDF]
Wei Y +9 more
europepmc +1 more source
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada +7 more
wiley +1 more source
Editorial: Water resource management using microbial solutions. [PDF]
Ji B.
europepmc +1 more source
Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley +1 more source
Injectable dual-affinity self-assembling peptide hydrogels for local controlled delivery of therapeutic antibodies. [PDF]
Cui W +8 more
europepmc +1 more source
CLA-GWO: A Bio-Inspired Closed-Loop Adaptive Grey Wolf Optimizer for the Traveling Salesman Problem. [PDF]
Wang S, Zhang Y, Kong X.
europepmc +1 more source
A dual membrane-adsorption evaporator for solar-powered lithium extraction from complex brines. [PDF]
Eskafi AF, Jiang W, Urban JJ, Mi B.
europepmc +1 more source
Synergistic PVA/zein electrospun nanofiber array with curcumin-alizarin: a water-resistant, sensitive colorimetric platform for graded pork freshness monitoring. [PDF]
Liu B +5 more
europepmc +1 more source

