Results 121 to 130 of about 352,668 (312)
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
On the New Hahn Sequence Space h(2)
Abstract and Applied AnalysisThis paper investigates the properties and structural characteristics of the new Hahn sequence space defined by using the second-order forward difference operator.
Orhan Tuğ
doaj +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
COLD FLOW TESTING OF DUAL-BELL NOZZLES IN ALTITUDE SIMULATION CHAMBERS
, 2005 DLR studied various subscale cold flow dual-bell nozzles at test facility P6.2. To fulfill future test requirements the facilitywas modified.
Böhm, Christian +3 more
core
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
The space of maximal Fourier multipliers as a dual space
, 2006 Figà-Talamanca characterized the space of Fourier multipliers as the dual space of a certain Banach space.
Tomita, Naohito
core
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
$n$-dual spaces associated to a normed space
, 2015 For a real normed space $X$, we study the $n$-dual space of $\left(X,\left\Vert \cdot \right\Vert \right) $ and show that the space is a Banach space. Meanwhile, for a real normed space $X$ of dimension $d\geq n$ which satisfies property (G), we discuss the $n$-dual space of $\left(X,\left\Vert \cdot,\ldots,\cdot \right\Vert _{G}\right) $, where ...
openaire +3 more sources
Groups with completely regular primitive dual space
, 1975 We show that if G is a unimodular, amenable group whose primitive dual space Pr C∗(G) satisfies certain regularity conditions, then G is in the class [FC]−.
Peters, Justin
core +1 more source