Results 111 to 120 of about 2,156,541 (254)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Multiplication between elements in martingale Hardy spaces and their dual spaces [PDF]

open access: yes
In this paper, we establish continuous bilinear decompositions that arise in the study of products between elements in martingale Hardy spaces Hp p0 ă p ⩽ 1q and functions in their dual spaces. Our decompositions are based on martingale paraproducts.
Bakas, O., Xu, Z, Zhai, Y., Zhang, H
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Fréchet spaces of continuous vector-valued functions: Complementability in dual Fréchet spaces and injectivity [PDF]

open access: yes, 1992
Fréchet spaces of strongly, weakly and weak*-continuous Fréchet space valued functions are considered. Complete solutions are given to the problems of their injectivity or embeddability as complemented subspaces in dual Fréchet ...
Domański, P., Drewnowski, L.
core  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

ON DUAL OF BANACH SEQUENCE SPACES

open access: yes, 2013
. J. Hagler and P. Azimi have introduced a class of Banach sequence spaces, the X α,1 spaces as a class of hereditarily 1 Banach spaces. In this paper, we show that (i) X * α,1 , the dual of Banach space X α,1 contains asymptotically isometric copies of ∞
V Parvaneh, A A Ledari
core  

Variable Fofana's Spaces and their Pre-dual

open access: yes, 2023
In this paper, we introduce the variable Fofana's spaces $(L^{p(\cdot)},L^q)^\alpha (\mathbb{R}^n)$ where $1< p(\cdot)
Zhou, Jiang, Yang, Fan
core  

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

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