Results 91 to 100 of about 646,982 (285)
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Carleson Measure and Tent Spaces on the Siegel Upper Half Space
Abstract and Applied Analysis, 2012 The Hausdorff capacity on the Heisenberg group is introduced. The Choquet integrals with respect to the Hausdorff capacity on the Heisenberg group are defined. Then the fractional Carleson measures on the Siegel upper half space are discussed.
Kai Zhao
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
The Application Domain of Infinite Matrices with Algorithms
Universal Journal of Mathematics and Applications, 2018 The purpose of this paper is twofold. First, we define the new spaces and investigate some topological and structural properties. Also, we compute dual spaces of new spaces which are help us in the characterization of matrix mappings.
Murat Kirişçi
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FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
On Generalized Difference Hahn Sequence Spaces
The Scientific World Journal, 2014 We construct some generalized difference Hahn sequence spaces by mean of sequence of modulus functions. The topological properties and some inclusion relations of spaces hpℱ,u,Δr are investigated. Also we compute the dual of these spaces, and some matrix
Kuldip Raj, Adem Kiliçman
doaj +1 more source
On almost B-summable double sequence spaces
Journal of Inequalities and Applications, 2018 The concept of a four-dimensional generalized difference matrix and its domain on some double sequence spaces was recently introduced and studied by Tuğ and Başar (AIP Conference Proceedings, vol. 1759, 2016) and Tuğ (J. Inequal. Appl. 2017(1):149, 2017).
Orhan Tuğ
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FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source