Results 81 to 90 of about 61,084 (264)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

On Generalized Difference Hahn Sequence Spaces

open access: yesThe Scientific World Journal, 2014
We construct some generalized difference Hahn sequence spaces by mean of sequence of modulus functions. The topological properties and some inclusion relations of spaces hpℱ,u,Δr are investigated. Also we compute the dual of these spaces, and some matrix
Kuldip Raj, Adem Kiliçman
doaj   +1 more source

On almost B-summable double sequence spaces

open access: yesJournal of Inequalities and Applications, 2018
The concept of a four-dimensional generalized difference matrix and its domain on some double sequence spaces was recently introduced and studied by Tuğ and Başar (AIP Conference Proceedings, vol. 1759, 2016) and Tuğ (J. Inequal. Appl. 2017(1):149, 2017).
Orhan Tuğ
doaj   +1 more source

The standard dual of an operator space [PDF]

open access: yesPacific Journal of Mathematics, 1992
If X is a linear space of operators on a Hilbert space, then it turns out that there is a natural, enlightening, nontrivial way to regard the dual \(X^*\) also as a linear space of operators on a (different) Hilbert space. The importance of this was pointed out in the work with \textit{V. I. Paulsen} [`Tensor products of operator spaces', J. Functional
openaire   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

New frames of Besov and Triebel-Lizorkin spaces

open access: yesJournal of Function Spaces and Applications, 2005
Let s≺0. The author obtains some new frames for Besov spaces Bpqs(ℝn) with 1≤p, q≤∞ and Triebel-Lizorkin spaces Fpqs(ℝn) with 1≺p≺∞ and 1≺q≤∞ by a dual method via the subatomic characterizations of these spaces when s≻0.
Dachun Yang
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

The doubled geometry of nilmanifold reductions

open access: yesJournal of High Energy Physics, 2019
A class of special holonomy spaces arise as nilmanifolds fibred over a line interval and are dual to intersecting brane solutions of string theory. Further dualities relate these to T-folds, exotic branes, essentially doubled spaces and spaces with R ...
N. Chaemjumrus, C.M. Hull
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

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