Results 61 to 70 of about 61,084 (264)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
International Journal of Mathematics and Mathematical Sciences, 1981 A Mazur space is a locally convex topological vector space X such that every fϵXs is continuous where Xs is the set of sequentially continuous linear functionals on X; Xs is studied when X is of the form C(H), H a topological space, and when X is the ...
Albert Wilansky
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Noncommutative Phase Spaces by Coadjoint Orbits Method
Symmetry, Integrability and Geometry: Methods and Applications, 2011 We introduce noncommutative phase spaces by minimal couplings (usual one, dual one and their mixing). We then realize some of them as coadjoint orbits of the anisotropic Newton-Hooke groups in two- and three-dimensional spaces.
Ancille Ngendakumana +2 more
doaj +1 more source
Some fixed point results for dual contractions of rational type [PDF]
Mathematica Moravica, 2017 Isik and Turkoglu [Some Fixed Point Theorems in Ordered Partial Metric Spaces, Journal of Inequalities and Special Functions, Volume 4 Issue 2(2013), Pages 13-18] established new fixed point results in complete partial metric spaces.
Nazam Muhammad +4 more
doaj
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
ON THE L-DUALITY OF A FINSLER SPACE WITH (\alpha ,\beta )-METRIC ( \alpha+\beta )^2/{\alpha} [PDF]
Romanian Journal of Mathematics and Computer Science, 2015 The geometry of higher order Finsler spaces were studied in ([1], [6], [10]). The theory of higher order Lagrange and Hamilton spaces were discussed in ([8], [9],[11]).
GAUREE SHANKER, DEEPTI CHOUDHARY
doaj
Two properties of Müntz spaces
Demonstratio Mathematica, 2017 We show that Müntz spaces, as subspaces of C[0, 1], contain asymptotically isometric copies of c0 and that their dual spaces are octahedral.
Abrahamsen Trond A. +3 more
doaj +1 more source