Results 41 to 50 of about 2,156,541 (254)
q-Stirling sequence spaces associated with q-Bell numbers
Open MathematicsIn this study, we build qq-analog of the qq-Stirling matrix involved qq-Bell numbers Sq=(Snk(q)){{\mathbb{S}}}_{q}=({S}_{nk}\left(q)) defined by Sq=(Snk(q))=Sq(n,k)Bq(n),0≤k≤n,0,otherwise.\begin{array}{r}{{\mathbb{S}}}_{q}=({S}_{nk}\left(q))=\left ...
Atabey Koray Ibrahim +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Nonstational Dual Wavelet Frames in Sobolev Spaces
, 2011 In view of the good properties of nonstationary wavelet frames and the better flexibility of wavelets in Sobolev spaces, the nonstationary dual wavelet frames in a pair of dual Sobolev spaces are studied in this paper.
Yan Tang, Yingchun Jiang
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Regularity of fuzzy convergence spaces
Open Mathematics, 2018 (Fuzzy) convergence spaces are extensions of (fuzzy) topological spaces. ⊤-convergence spaces are one of important fuzzy convergence spaces. In this paper, we present an extending dual Fischer diagonal condition, and making use of this we discuss a ...
Li Lingqiang, Jin Qiu, Yao Bingxue
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Linear programming bounds for doubly-even self-dual codes [PDF]
, 1997 Using a variant of linear programming method we derive a new upper bound on the minimum distance d of doubly-even self-dual codes of length n. Asymptotically, for n growing, it gives d/n
Krasikov, I +4 more
core +2 more sources
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Multi-graded Macaulay Dual Spaces [PDF]
, 2023 We describe an algorithm for computing Macaulay dual spaces for multi-graded ideals. For homogeneous ideals, the natural grading is inherited by the Macaulay dual space which has been leveraged to develop algorithms to compute the Macaulay dual space in ...
Cummings, Joseph, Hauenstein, Jonathan
core